Correlation between Three-Dimensional Volume and Malignant Potential of Gastrointestinal Stromal Tumors (GISTs)
Abstract
:1. Introduction
2. Materials and Methods
2.1. Study Design
2.2. Data Source
2.3. Outcomes
2.4. Statistical Analysis
3. Results
3.1. Clinical Characteristics of Patients with GISTs
3.2. Clinical Characteristics of Patients with Recurrent GISTs
3.3. Multivariate Analysis of the Malignant Potential of GISTs
3.4. Receiver Operating Characteristic (ROC) Curve of the Malignant Potential of GISTs
4. Discussion
Author Contributions
Funding
Conflicts of Interest
References
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Benign GIST (n = 64) | Malignant GIST (n = 6) | p | |
---|---|---|---|
Age | 57.77 ± 11.79 | 60.83 ± 20.57 | 0.032 |
Sex | |||
Men | 30 (46.9%) | 4 (66.7%) | 0.354 |
Women | 34 (53.1%) | 2 (33.3%) | |
Location | |||
Stomach | 51 (80.0%) | 2 (33.3%) | 0.011 |
Non-stomach | 13 (20.0%) | 4 (66.7%) | |
Mitoses | |||
Less than 5 | 52 (81.3%) | 4 (66.7%) | 0.393 |
5 or more | 12 (18.7%) | 2 (33.3%) | |
Long axis (mm) | 35.40 ± 22.38 | 73.33 ± 38.04 | 0.073 |
Volume (cm3) | 53.07 ± 142.84 | 270.67 ± 410.80 | 0.001 |
Necrosis | 9 (14.1%) | 4 (66.7%) | 0.001 |
No Recurrence (n = 44) | Recurrence (n = 4) | p | |
---|---|---|---|
Age | 58.41 ± 10.81 | 61.00 ± 19.65 | 0.045 |
Sex | |||
Men | 20 (45.5%) | 3 (75.0%) | 0.257 |
Women | 24 (54.5%) | 1 (25.0%) | |
Follow-up period (year) | 3.84 ± 2.73 | 3.75 ± 1.26 | 0.950 |
Location | |||
Stomach | 36 (81.8%) | 0 (0.0%) | 0.000 |
Non-stomach | 8 (18.2%) | 4 (100.0%) | |
Mitoses | |||
Less than 5 | 33 (75.0%) | 3 (75.0%) | 1.000 |
5 or more | 11 (25.0%) | 1 (25.0%) | |
Long axis (mm) | 33.67 ± 25.08 | 72.49 ± 22.01 | 0.005 |
Volume (cm3) | 56.25 ± 188.37 | 240.96 ± 242.38 | 0.072 |
Variable | Odd Ratio (95% CI) | p |
---|---|---|
Age | 1.020 (0.953–1.092) | 0.567 |
Location | ||
Stomach | Reference | 0.025 |
Non-stomach | 7.846 (1.293–47.624) | |
Long axis | 1.037 (1.011–1.065) | 0.006 |
Volume | 1.003 (1.000–1.006) | 0.029 |
Long axis | ||
Less than 5cm | Reference | 0.009 |
Above 5cm | 11.778 (1.873–74.05) | |
Necrosis | 12.222 (1.945–76.794) | 0.008 |
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Park, J.H.; Kang, B.-k.; Lee, H.L.; Yoon, J.H.; Lee, K.N.; Jun, D.W.; Lee, O.Y.; Han, D.S.; Yoon, B.C.; Choi, H.S. Correlation between Three-Dimensional Volume and Malignant Potential of Gastrointestinal Stromal Tumors (GISTs). J. Clin. Med. 2020, 9, 2763. https://doi.org/10.3390/jcm9092763
Park JH, Kang B-k, Lee HL, Yoon JH, Lee KN, Jun DW, Lee OY, Han DS, Yoon BC, Choi HS. Correlation between Three-Dimensional Volume and Malignant Potential of Gastrointestinal Stromal Tumors (GISTs). Journal of Clinical Medicine. 2020; 9(9):2763. https://doi.org/10.3390/jcm9092763
Chicago/Turabian StylePark, Jin Hwa, Bo-kyeong Kang, Hang Lak Lee, Jai Hoon Yoon, Kang Nyeong Lee, Dae Won Jun, Oh Young Lee, Dong Soo Han, Byung Chul Yoon, and Ho Soon Choi. 2020. "Correlation between Three-Dimensional Volume and Malignant Potential of Gastrointestinal Stromal Tumors (GISTs)" Journal of Clinical Medicine 9, no. 9: 2763. https://doi.org/10.3390/jcm9092763