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Open AccessReview

New Antithrombotic Drugs in Acute Coronary Syndrome

Department of Cardiology, St. Antonius Hospital, 3435 CM Nieuwegein, The Netherlands
Department of Cardiology, Catharina Hospital, 5623 EJ Eindhoven, The Netherlands
Cardiovascular Research Unit, Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield S10 2RX, UK
South Yorkshire Cardiothoracic Centre, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield S5 7AU, UK
Author to whom correspondence should be addressed.
J. Clin. Med. 2020, 9(7), 2059;
Received: 29 May 2020 / Revised: 25 June 2020 / Accepted: 27 June 2020 / Published: 30 June 2020
(This article belongs to the Special Issue Antithrombotic Treatment of Acute Coronary Syndrome)
In recent years, much progress has been made in the field of antithrombotic drugs in acute coronary syndrome (ACS) treatment, as reflected by the introduction of the more potent P2Y12-inhibitors prasugrel and ticagrelor, and novel forms of concomitant anticoagulation, such as fondaparinux and bivalirudin. However, despite substantial improvements in contemporary ACS treatment, there remains residual ischemic risk in this group and hence the need for even more effective antithrombotic drugs, while balancing antithrombotic efficacy against bleeding risk. This review discusses recently introduced and currently developed antiplatelet and anticoagulant drugs in ACS treatment. View Full-Text
Keywords: acute coronary syndrome; platelets; antithrombotic drugs acute coronary syndrome; platelets; antithrombotic drugs
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Zwart, B.; Parker, W.A.E.; Storey, R.F. New Antithrombotic Drugs in Acute Coronary Syndrome. J. Clin. Med. 2020, 9, 2059.

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