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Open AccessArticle

Left Atrial Volumetric and Deformation Analysis in Adult Patients with Dextro-Transposition of the Great Arteries (Insights from the CSONGRAD Registry and MAGYAR-Path Study)

2nd Department of Medicine and Cardiology Centre, Medical Faculty, Albert Szent-Györgyi Clinical Center, University of Szeged, H-6725 Szeged, Hungary
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J. Clin. Med. 2020, 9(2), 463; https://doi.org/10.3390/jcm9020463
Received: 15 January 2020 / Revised: 31 January 2020 / Accepted: 4 February 2020 / Published: 7 February 2020
Background: In complete or dextro-transposition of the great arteries (dTGA), the aorta and the pulmonary artery are transposed. The present study was designed to examine dTGA-associated left atrial (LA) volumetric and functional abnormalities in adult patients late after repair and to compare their results to those of healthy controls. Methods: The present study consisted of 15 dTGA patients (30.3 ± 8.1 years, 9 males), the patients had Mustard (n = 8) or Senning (n = 7) procedure performed. Their results were compared to those of 36 age- and gender-matched healthy subjects (28.7 ± 1.5 years, 24 males). Results: Increased maximum LA volume and reduced LA emptying fractions respecting the cardiac cycle could be demonstrated in our dTGA patients. LA stroke volumes representing all LA functions were significantly reduced. Peak LA circumferential, longitudinal, and area strains and LA circumferential, longitudinal, and area strains measured at atrial contraction were reduced in our dTGA patients. Most LA strains were reduced in patients having Mustard surgery compared to controls and patients undergoing Senning operation. Conclusions: Significant LA volumetric and functional abnormalities could be demonstrated in adult patients with dTGA late after repair. Senning procedure seems to have more beneficial long-term effects on LA volumetric and functional features as compared to the Mustard procedure. View Full-Text
Keywords: left atrium; function; two-dimensional; three-dimensional; echocardiography; speckle-tracking; transposition of the great arteries left atrium; function; two-dimensional; three-dimensional; echocardiography; speckle-tracking; transposition of the great arteries
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MDPI and ACS Style

Nemes, A.; Rácz, G.; Kormányos, Á.; Domsik, P.; Kalapos, A.; Gyenes, N.; Ambrus, N.; Bogáts, G.; Hartyánszky, I.; Havasi, K. Left Atrial Volumetric and Deformation Analysis in Adult Patients with Dextro-Transposition of the Great Arteries (Insights from the CSONGRAD Registry and MAGYAR-Path Study). J. Clin. Med. 2020, 9, 463. https://doi.org/10.3390/jcm9020463

AMA Style

Nemes A, Rácz G, Kormányos Á, Domsik P, Kalapos A, Gyenes N, Ambrus N, Bogáts G, Hartyánszky I, Havasi K. Left Atrial Volumetric and Deformation Analysis in Adult Patients with Dextro-Transposition of the Great Arteries (Insights from the CSONGRAD Registry and MAGYAR-Path Study). Journal of Clinical Medicine. 2020; 9(2):463. https://doi.org/10.3390/jcm9020463

Chicago/Turabian Style

Nemes, Attila; Rácz, Gergely; Kormányos, Árpád; Domsik, Péter; Kalapos, Anita; Gyenes, Nándor; Ambrus, Nóra; Bogáts, Gábor; Hartyánszky, István; Havasi, Kálmán. 2020. "Left Atrial Volumetric and Deformation Analysis in Adult Patients with Dextro-Transposition of the Great Arteries (Insights from the CSONGRAD Registry and MAGYAR-Path Study)" J. Clin. Med. 9, no. 2: 463. https://doi.org/10.3390/jcm9020463

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