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Article

Postprandial Hypotension as a Risk Factor for the Development of New Cardiovascular Disease: A Prospective Cohort Study with 36 Month Follow-Up in Community-Dwelling Elderly People

Department of Nursing, University of Ulsan, 93, Daehak-ro, Nam-gu, Ulsan 44610, Korea
J. Clin. Med. 2020, 9(2), 345; https://doi.org/10.3390/jcm9020345
Received: 2 January 2020 / Revised: 21 January 2020 / Accepted: 23 January 2020 / Published: 27 January 2020
(This article belongs to the Special Issue Clinical Medicine for Healthcare and Sustainability)
Postprandial hypotension (PPH) is common among the elderly. However, it is unknown whether the presence of PPH can predict the development of new cardiovascular disease (CVD) in the elderly during the long-term period. This study aimed to prospectively evaluate the presence of PPH and the development of new CVD within a 36 month period in 94 community-dwelling elderly people without a history of CVD. PPH was diagnosed in 47 (50.0%) participants at baseline and in 7 (7.4%) during the follow-up period. Thirty participants (31.9%) developed new CVD within 36 months. We performed a time-dependent Cox regression analysis with PPH, hypertension, diabetes, and body mass index (BMI) as time-varying covariates. In the univariate analyses, the presence of PPH, higher BMI, hypertension, diabetes mellitus, and higher systolic and diastolic blood pressure were associated with the development of new CVD. The multivariate analysis indicated that the relationship between PPH and the development of new CVD remained (adjusted hazard ratio 11.18, 95% confidence interval 2.43–51.38, p = 0.002) even after controlling for other variables as covariates. In conclusion, the presence of PPH can predict the development of new CVD. Elderly people with PPH may require close surveillance to prevent CVD. View Full-Text
Keywords: cardiovascular disease; postprandial; hypotension; blood pressure; elderly cardiovascular disease; postprandial; hypotension; blood pressure; elderly
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MDPI and ACS Style

Jang, A. Postprandial Hypotension as a Risk Factor for the Development of New Cardiovascular Disease: A Prospective Cohort Study with 36 Month Follow-Up in Community-Dwelling Elderly People. J. Clin. Med. 2020, 9, 345. https://doi.org/10.3390/jcm9020345

AMA Style

Jang A. Postprandial Hypotension as a Risk Factor for the Development of New Cardiovascular Disease: A Prospective Cohort Study with 36 Month Follow-Up in Community-Dwelling Elderly People. Journal of Clinical Medicine. 2020; 9(2):345. https://doi.org/10.3390/jcm9020345

Chicago/Turabian Style

Jang, Aelee. 2020. "Postprandial Hypotension as a Risk Factor for the Development of New Cardiovascular Disease: A Prospective Cohort Study with 36 Month Follow-Up in Community-Dwelling Elderly People" Journal of Clinical Medicine 9, no. 2: 345. https://doi.org/10.3390/jcm9020345

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