Eosinophilic Esophagitis in Children in North-Eastern Poland
Abstract
:1. Introduction
2. Materials and Methods
3. Results
4. Discussion
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Conflicts of Interest
References
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EoE Group | Non-EoE Group | p Value | |
---|---|---|---|
Number of patients | 36 (8.31%) | 397 (91.7%) | - |
Age (year) | 10 (2–17) | 13 (1–18) | <0.001 |
Male (n) | 28 (77.78%) | 197 (49.62%) | 0.002 |
BMI | |||
<10 percentile | 10 (27.78%) | 73 (18.39%) | NS |
>90 percentile | 3 (8.33%) | 46 (11.59%) | NS |
Co-existing conditions | |||
Food allergy | 4 (11.11%) | 10 (2.52%) | 0.02 |
Seasonal allergy | 9 (23.08%) | 35 (8.82%) | 0.005 |
Diabetes mellitus type 1 | 0 (0%) | 1 (0.25%) | NA |
Celiac disease | 4 (11.11%) | 28 (6.30%) | NS |
IBD | 4 (11.11%) | 23 (5.79%) | NS |
Symptoms | |||
Abdominal pain (n) | 25 (69.4%) | 297 (74.81%) | NS |
Failure of thrive (n) | 11 (30.6%) | 76 (19.14%) | NS |
Dysphagia (n) | 8 (22.2%) | 29 (7.30%) | 0.006 |
Halitosis (n) | 7 (19.4%) | 51 (12.85%) | NS |
Vomiting (n) | 6 (16.7%) | 89 (22.42%) | NS |
Lack of appetite (n) | 6 (16.7%) | 54 (13.60%) | NS |
Heartburn (n) | 1 (2.78%) | 42 (10.58%) | NS |
Nausea (n) | 3 (8.33%) | 65 (16.37%) | NS |
Weight loss (n) | 2 (5.56%) | 45 (11.34%) | NS |
Eructation (n) | 3 (8.33%) | 55 (13.85%) | NS |
Regurgitation (n) | 2 (5.56%) | 9 (2.28%) | NS |
Chest pain (n) | 0 (0%) | 10 (2.52%) | NA |
EoE | Non-EoE | p | |
---|---|---|---|
Endoscopy and histology findings | |||
Longitudinal furrowing (n) | 25 (69.4%) | 19 (4.76%) | <0.001 |
Decrease vascular pattern (n) | 11 (30.6%) | 18 (4.53%) | <0.001 |
Whitish exudates (n) | 7 (19.4%) | 9 (2.37%) | <0.001 |
Esophageal erosion (n) | 5 (13.89%) | 40 (10.08%) | NS |
Mucosal esophageal erythema (n) | 4 (11.11%) | 41 (10.33%) | NS |
Papules/plaques (n) | 4 (11.11%) | 46 (11.59%) | NS |
Trachealization/rings (n) | 3 (8.33%) | 5 (1.26%) | 0.02 |
Esophageal polyp (n) | 1 (2.78%) | 6 (1.51%) | NS |
Esophageal hernia (n) | 3 (8.33%) | 36 (9.07%) | NS |
Helicobacter pylori infection (n) | 16 (44.44%) | 181 (45.59%) | NS |
Median eosinophil counts (range) | 22 (15–45) | 0 (0–12) | - |
Number of endoscopic changes: | |||
0 | 4 (11.11%) | 249 (65.70%) | <0.001 |
1 | 10 (27.78%) | 91 (24.01%) | NS |
2 | 14 (38.89%) | 43 (11.35%) | <0.001 |
3 | 7 (19.44%) | 10 (2.52%) | <0.001 |
Laboratory results | |||
Eosinophilia (n) (>400 eos/μL) | 20 (55.56%) | 26 (6.55%) | <0.001 |
Hb (median, min-max) (g/dL) | 13.05 (10.7–17.0) | 13.30 (8.1–17.2) | NS |
CRP (median, min-max) (mg/dL) | 0.2 (0.0–4.8) | 0.2(0.0–52.1) | NS |
PLT (median, min-max) (×103/μL) | 253 (152–439) | 266 (86–643) | NS |
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Zdanowicz, K.; Kucharska, M.; Sobaniec-Lotowska, M.E.; Lebensztejn, D.M.; Daniluk, U. Eosinophilic Esophagitis in Children in North-Eastern Poland. J. Clin. Med. 2020, 9, 3869. https://doi.org/10.3390/jcm9123869
Zdanowicz K, Kucharska M, Sobaniec-Lotowska ME, Lebensztejn DM, Daniluk U. Eosinophilic Esophagitis in Children in North-Eastern Poland. Journal of Clinical Medicine. 2020; 9(12):3869. https://doi.org/10.3390/jcm9123869
Chicago/Turabian StyleZdanowicz, Katarzyna, Magdalena Kucharska, Maria Elzbieta Sobaniec-Lotowska, Dariusz Marek Lebensztejn, and Urszula Daniluk. 2020. "Eosinophilic Esophagitis in Children in North-Eastern Poland" Journal of Clinical Medicine 9, no. 12: 3869. https://doi.org/10.3390/jcm9123869
APA StyleZdanowicz, K., Kucharska, M., Sobaniec-Lotowska, M. E., Lebensztejn, D. M., & Daniluk, U. (2020). Eosinophilic Esophagitis in Children in North-Eastern Poland. Journal of Clinical Medicine, 9(12), 3869. https://doi.org/10.3390/jcm9123869