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Optical Coherence Tomography Angiography Imaging in Inherited Retinal Diseases

Wilmer Eye Institute, Johns Hopkins Hospital, Baltimore, MD 21287, USA
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Author to whom correspondence should be addressed.
J. Clin. Med. 2019, 8(12), 2078; https://doi.org/10.3390/jcm8122078
Received: 27 October 2019 / Accepted: 20 January 2019 / Published: 28 November 2019
(This article belongs to the Special Issue Application of Retinal and Optic Nerve Imaging in Clinical Medicine)
Optical coherence tomography angiography (OCTA) is a novel, noninvasive imaging modality that allows depth-resolved imaging of the microvasculature in the retina and the choroid. It is a powerful research tool to study the pathobiology of retinal diseases, including inherited retinal dystrophies. In this review, we provide an overview of the evolution of OCTA technology, compare the specifications of various OCTA devices, and summarize key findings from published OCTA studies in inherited retinal dystrophies including retinitis pigmentosa, Stargardt disease, Best vitelliform macular dystrophy, and choroideremia. OCTA imaging has provided new data on characteristics of these conditions and has contributed to a deeper understanding of inherited retinal disease.
Keywords: optical coherence tomography angiography; degenerative retinal diseases; retinitis pigmentosa; Stargardt disease; Best disease; choroideremia; gene therapy; retinal pigment epithelium; in vivo imaging; choriocapillaris optical coherence tomography angiography; degenerative retinal diseases; retinitis pigmentosa; Stargardt disease; Best disease; choroideremia; gene therapy; retinal pigment epithelium; in vivo imaging; choriocapillaris
MDPI and ACS Style

Ong, S.S.; Patel, T.P.; Singh, M.S. Optical Coherence Tomography Angiography Imaging in Inherited Retinal Diseases. J. Clin. Med. 2019, 8, 2078.

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