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Review of the Latest Percutaneous Devices in Critical Limb Ischemia

1
Department of Internal Medicine, Yale-New Haven Hospital, New Haven, CT 06520 USA
2
Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06520, USA
*
Author to whom correspondence should be addressed.
J. Clin. Med. 2018, 7(4), 82; https://doi.org/10.3390/jcm7040082
Received: 30 March 2018 / Revised: 10 April 2018 / Accepted: 10 April 2018 / Published: 14 April 2018
(This article belongs to the Special Issue Advances in Interventional Cardiology and Vascular Medicine)
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PDF [222 KB, uploaded 3 May 2018]

Abstract

Critical limb ischemia (CLI) is a terminal stage of peripheral arterial disease that, in the absence of intervention, may lead to lower extremity amputation or death. Endovascular interventions have become a first-line approach to the management of CLI and have advanced considerably within the past decade. This review summarizes the types of percutaneous devices and the techniques that are available for the management of CLI and the data supporting their use. These include devices that establish and maintain vessel patency, including percutaneous transluminal angioplasty, drug-coated balloons, bare metal stents, drug-eluting stents, bioresorbable vascular scaffolds, and atherectomy; devices that provide protection from embolization; and, cell-based therapies. Additionally, ongoing trials with important implications for the field are discussed. View Full-Text
Keywords: critical limb ischemia; peripheral artery disease; percutaneous transluminal angioplasty; drug-coated balloons; bare metal stents; drug-eluting stents; atherectomy; cryoplasty; embolic protection devices critical limb ischemia; peripheral artery disease; percutaneous transluminal angioplasty; drug-coated balloons; bare metal stents; drug-eluting stents; atherectomy; cryoplasty; embolic protection devices
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
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Haghighat, L.; Altin, S.E.; Attaran, R.R.; Mena-Hurtado, C.; Regan, C.J. Review of the Latest Percutaneous Devices in Critical Limb Ischemia. J. Clin. Med. 2018, 7, 82.

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