Mitochondrial Glutathione in Diabetic Nephropathy
Abstract
:1. Introduction
2. Determination of mtGSH Status: Transport versus Synthesis and Identification of Carriers
2.1. Background and Identification of mtGSH Carriers in Renal Mitochondria
2.2. Function of the DIC and OGC Demonstrated in Mitochondria from Other Tissues
2.3. Do the DIC and OGC Really Transport GSH into Mitochondria?
3. Cellular and mtGSH in Diabetic Nephropathy and Other Renal Diseases Involving Tubular Epithelial Cell Hypertrophy
3.1. Diabetic Nephropathy
3.2. Uninephrectomy and Compensatory Renal Hypertrophy
4. Toxicological Impact of Varying mtGSH Transport
5. Summary and Conclusions
Acknowledgments
Author Contributions
Conflicts of Interest
References
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Lash, L.H. Mitochondrial Glutathione in Diabetic Nephropathy. J. Clin. Med. 2015, 4, 1428-1447. https://doi.org/10.3390/jcm4071428
Lash LH. Mitochondrial Glutathione in Diabetic Nephropathy. Journal of Clinical Medicine. 2015; 4(7):1428-1447. https://doi.org/10.3390/jcm4071428
Chicago/Turabian StyleLash, Lawrence H. 2015. "Mitochondrial Glutathione in Diabetic Nephropathy" Journal of Clinical Medicine 4, no. 7: 1428-1447. https://doi.org/10.3390/jcm4071428