Intralesional Corticosteroid Injections in the Treatment of Oral Lichen Planus—A Narrative Review

Miazga-Rychlik, Weronika; Milczarek, Emilia; Kowalski, Jan; Brodzikowska, Aniela; Górski, Bartłomiej

doi:10.3390/jcm15020561

Open AccessReview

Intralesional Corticosteroid Injections in the Treatment of Oral Lichen Planus—A Narrative Review

by

Weronika Miazga-Rychlik

^1,*

,

Emilia Milczarek

¹,

Jan Kowalski

¹,

Aniela Brodzikowska

²

and

Bartłomiej Górski

¹

Department of Periodontology and Oral Mucosa Diseases, Medical University of Warsaw, 6 Binieckiego St., 02-097 Warsaw, Poland

²

Department of Conservative Dentistry, Medical University of Warsaw, 6 Binieckiego St., 02-097 Warsaw, Poland

^*

Author to whom correspondence should be addressed.

J. Clin. Med. 2026, 15(2), 561; https://doi.org/10.3390/jcm15020561

Submission received: 28 November 2025 / Revised: 5 January 2026 / Accepted: 6 January 2026 / Published: 9 January 2026

(This article belongs to the Special Issue Paradigms, Advances and Future Directions in Oral Medicine)

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Abstract

Background: Oral lichen planus (OLP) is a chronic inflammatory autoimmune disease. Certain clinical forms of the disease may cause significant discomfort and negatively impact patients’ quality of life. The first-line treatment is topical corticosteroids. The purpose of this narrative review is to evaluate the influence of corticosteroid injections in the treatment of OLP. Methods: A search of the literature was conducted in October 2025 using the following databases: PubMed, Web of Science, Scopus, and Cochrane. Results: Fifteen studies were evaluated. Injections with triamcinolone acetonide at a concentration of 10–40 mg/mL at weekly intervals demonstrated efficacy in reducing pain and healing OLP lesions in these studies. They showed minor adverse effects. Conclusions: Noting the limitations of this narrative review, intralesional corticosteroid injections are an effective and safe method of treating OLP. They should be considered in patients with symptomatic OLP.

Keywords: oral lichen planus; corticosteroid injections; triamcinolone acetonide

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MDPI and ACS Style

Miazga-Rychlik, W.; Milczarek, E.; Kowalski, J.; Brodzikowska, A.; Górski, B. Intralesional Corticosteroid Injections in the Treatment of Oral Lichen Planus—A Narrative Review. J. Clin. Med. 2026, 15, 561. https://doi.org/10.3390/jcm15020561

AMA Style

Miazga-Rychlik W, Milczarek E, Kowalski J, Brodzikowska A, Górski B. Intralesional Corticosteroid Injections in the Treatment of Oral Lichen Planus—A Narrative Review. Journal of Clinical Medicine. 2026; 15(2):561. https://doi.org/10.3390/jcm15020561

Chicago/Turabian Style

Miazga-Rychlik, Weronika, Emilia Milczarek, Jan Kowalski, Aniela Brodzikowska, and Bartłomiej Górski. 2026. "Intralesional Corticosteroid Injections in the Treatment of Oral Lichen Planus—A Narrative Review" Journal of Clinical Medicine 15, no. 2: 561. https://doi.org/10.3390/jcm15020561

APA Style

Miazga-Rychlik, W., Milczarek, E., Kowalski, J., Brodzikowska, A., & Górski, B. (2026). Intralesional Corticosteroid Injections in the Treatment of Oral Lichen Planus—A Narrative Review. Journal of Clinical Medicine, 15(2), 561. https://doi.org/10.3390/jcm15020561

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

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Intralesional Corticosteroid Injections in the Treatment of Oral Lichen Planus—A Narrative Review

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