Next Article in Journal
Impact of Femoral Morphology and Stem Design on Intraoperative Periprosthetic Femoral Fractures in Cementless Total Hip Arthroplasty
Next Article in Special Issue
Beyond Recanalization: A Mechanistic and Procedural Framework for Adjunct Pharmacologic Therapy During Mechanical Thrombectomy
Previous Article in Journal
Open and Percutaneous Fixation of Traumatic Sacral Fracture–Dislocation with Spinopelvic Dissociation: Two Adolescent Cases and a Systematic Literature Review
Previous Article in Special Issue
Construction and Validation of a 90-Day Mortality Risk Prediction Model Based on Interpretable Machine Learning for Acute Ischemic Stroke Patients Undergoing Mechanical Thrombectomy
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
JCM
Volume 15
Issue 13
10.3390/jcm15134916
jcm-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Article

Impact of Anesthesia Modality on Clinical Outcomes in Anterior Circulation Stroke Patients Undergoing Mechanical Thrombectomy: A Retrospective Propensity Score-Matched Analysis

by
Mustafa Çetiner
1,*,
Ayşe Nur Akca
1,
Gönül Akdağ
1,
Buse Kozlu
2,
İrem Yıldırım
1,
Abdulhamit Şehid Kılınç
2,
Esma Aşık
3,
Burcu Kaplan
2,
Fahri Şen
2 and
Nurullah Can Aydoğdu
1
1
Department of Neurology, Faculty of Medicine, Kütahya Health Sciences University, Kütahya 43000, Türkiye
2
Department of Anesthesiology and Reanimation, Kütahya Evliya Çelebi Training and Research Hospital, Kütahya 43000, Türkiye
3
Department of Algology, Faculty of Medicine, Ege University, İzmir 35000, Türkiye
*
Author to whom correspondence should be addressed.
J. Clin. Med. 2026, 15(13), 4916; https://doi.org/10.3390/jcm15134916
Submission received: 18 May 2026 / Revised: 12 June 2026 / Accepted: 20 June 2026 / Published: 24 June 2026
(This article belongs to the Special Issue Acute Ischemic Stroke Management Strategies)
Browse Figures
Versions Notes

Abstract

Background/Objectives: The type of anesthesia in patients with acute stroke is still controversial. This study aimed to investigate the effect of anesthesia management on clinical outcomes in patients with anterior circulation stroke undergoing mechanical thrombectomy. Methods: In this observational, retrospective study, patients with acute anterior circulation stroke who underwent mechanical thrombectomy between January 2021 and March 2025 were retrospectively reviewed. Patients were divided into groups according to the type of anesthesia administered. Functional independence was assessed at 90 days using the modified Rankin Scale. A TICI of 2b or higher was defined as successful reperfusion. In the conscious sedation (CS) and general anesthesia (GA) groups, patients were analyzed based on baseline characteristics and clinical outcomes using Propensity Score Matching. Results: In the propensity score-matched cohort, there was no significant difference between the two groups in terms of good functional outcome (mRS ≤ 2) (p = 0.82). When compared by successful reperfusion rate (TICI 2b or higher), it was significantly higher in the GA group (p = 0.01). Conclusions: In this study, the use of GA resulted in higher recanalization rates in patients with anterior circulation stroke undergoing mechanical thrombectomy. However, no differences were observed between the GA and CS groups in terms of functional outcomes, mortality, or peri-procedural/post-procedural complications.
Keywords: ischemic stroke; anesthesia; thrombectomy ischemic stroke; anesthesia; thrombectomy

Share and Cite

MDPI and ACS Style

Çetiner, M.; Akca, A.N.; Akdağ, G.; Kozlu, B.; Yıldırım, İ.; Kılınç, A.Ş.; Aşık, E.; Kaplan, B.; Şen, F.; Aydoğdu, N.C. Impact of Anesthesia Modality on Clinical Outcomes in Anterior Circulation Stroke Patients Undergoing Mechanical Thrombectomy: A Retrospective Propensity Score-Matched Analysis. J. Clin. Med. 2026, 15, 4916. https://doi.org/10.3390/jcm15134916

AMA Style

Çetiner M, Akca AN, Akdağ G, Kozlu B, Yıldırım İ, Kılınç AŞ, Aşık E, Kaplan B, Şen F, Aydoğdu NC. Impact of Anesthesia Modality on Clinical Outcomes in Anterior Circulation Stroke Patients Undergoing Mechanical Thrombectomy: A Retrospective Propensity Score-Matched Analysis. Journal of Clinical Medicine. 2026; 15(13):4916. https://doi.org/10.3390/jcm15134916

Chicago/Turabian Style

Çetiner, Mustafa, Ayşe Nur Akca, Gönül Akdağ, Buse Kozlu, İrem Yıldırım, Abdulhamit Şehid Kılınç, Esma Aşık, Burcu Kaplan, Fahri Şen, and Nurullah Can Aydoğdu. 2026. "Impact of Anesthesia Modality on Clinical Outcomes in Anterior Circulation Stroke Patients Undergoing Mechanical Thrombectomy: A Retrospective Propensity Score-Matched Analysis" Journal of Clinical Medicine 15, no. 13: 4916. https://doi.org/10.3390/jcm15134916

APA Style

Çetiner, M., Akca, A. N., Akdağ, G., Kozlu, B., Yıldırım, İ., Kılınç, A. Ş., Aşık, E., Kaplan, B., Şen, F., & Aydoğdu, N. C. (2026). Impact of Anesthesia Modality on Clinical Outcomes in Anterior Circulation Stroke Patients Undergoing Mechanical Thrombectomy: A Retrospective Propensity Score-Matched Analysis. Journal of Clinical Medicine, 15(13), 4916. https://doi.org/10.3390/jcm15134916

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

Article Metrics

Back to TopTop