Next Article in Journal
From Bailout to Benchmark? Rethinking the Alfieri Procedure for Mitral Regurgitation in Barlow’s Disease
Previous Article in Journal
Prehabilitation Before Cardiac Surgery and Structural Heart Interventions: An Umbrella Review of Pooled Evidence
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
JCM
Volume 15
Issue 10
10.3390/jcm15103819
jcm-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
This is an early access version, the complete PDF, HTML, and XML versions will be available soon.
Article

Dialysis on the Central Venous Catheter at the Time of Arteriovenous Fistula Creation Is Associated with Long-Term Vascular Access Failure

by
Eliza Russu
1,2,
Réka Bartus
1,2,*,
Elena Florea
3,
Alexandru Mureșan
2,
Paula Bândea
2,
Paul Mateica
2,
Ionela Georgiana Tofana
2,
Constantin Claudiu Ciucanu
1,2,3,
Eliza-Mihaela Arbănași
3,4,
Alexandru Petru Ion
3,4,
Paula Chirilă
3,
Ioan Hosu
5,
Mirela Liana Gliga
5,6,7,
Adrian Vasile Mureșan
1,2 and
Emil-Marian Arbănași
1,2,3,4
1
Department of Vascular Surgery, George Emil Palade University of Medicine, Pharmacy, Science and Technology of Targu Mures, 540142 Targu Mures, Romania
2
Clinic of Vascular Surgery, Mures County Emergency Hospital, 540136 Targu Mures, Romania
3
Doctoral School of Medicine and Pharmacy, George Emil Palade University of Medicine, Pharmacy, Science and Technology of Targu Mures, 540142 Targu Mures, Romania
4
Regenerative Medicine Laboratory, Centre for Advanced Medical and Pharmaceutical Research (CCAMF), George Emil Palade University of Medicine, Pharmacy, Science and Technology of Targu Mures, 540142 Targu Mures, Romania
5
Department of Internal Medicine-Nephrology, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures, 540142 Targu Mures, Romania
6
Department of Nephrology, Mures Clinical County Hospital, 540139 Targu Mures, Romania
7
Diaverum Dialysis Center, 540139 Targu Mures, Romania
*
Author to whom correspondence should be addressed.
J. Clin. Med. 2026, 15(10), 3819; https://doi.org/10.3390/jcm15103819
Submission received: 10 April 2026 / Revised: 12 May 2026 / Accepted: 13 May 2026 / Published: 15 May 2026
(This article belongs to the Section Vascular Medicine)
Versions Notes

Abstract

Background/Objectives: The autologous arteriovenous fistula (AVF) is the primary vascular access (VA) method for hemodialysis (HD), with superior patency and a lower complication rate than arteriovenous graft (AVG) or central venous catheter (CVC). The primary objective of this study is to analyze the impact of dialysis on the CVC at the time of AVF creation on its long-term primary patency. Methods: This retrospective, single-center, observational study included 248 patients admitted for AVF creation. Demographic characteristics, comorbid conditions, and laboratory parameters were retrieved from the hospital’s electronic medical records. The primary outcome of the study was long-term AVF failure, defined as the inability to perform hemodialysis through the newly created AVF. Results: A total of 132 (53.2%) were receiving dialysis via a CVC at the time of AVF creation. During a mean follow-up of 2.21 ± 1.54 years, 47 patients (18.95%) failed to achieve functional maturation at 6 weeks, and 81 patients (32.66%) developed long-term AVF failure. Demographic characteristics were similar between patients with and without CVC at AVF creation, with no significant differences in age (p = 0.358) or sex (p = 0.574). Comorbidities and risk factors were also similarly distributed, showing no significant variation. The types of AVF varied by CVC status, with fewer RC-AVF (p = 0.038) and more BC-AVF (p = 0.032) in patients with a CVC. Failure was significantly more frequent in patients with CVC use at the time of AVF creation than in those without CVC (p < 0.001). Kaplan–Meier analysis demonstrated lower long-term patency in patients dialyzed via CVC (p < 0.001). In Cox regression analysis, dialysis via CVC at AVF creation was associated with AVF failure (HR: 2.53, p < 0.001), and the association remained significant after full adjustment (HR: 3.13, p < 0.001). Female sex, active smoking, smaller arterial and venous diameters, and RC-AVF were additional risk factors associated with failure. Conclusions: Dialysis via a CVC at the time of AVF creation was associated with an increased risk of long-term AVF failure, even after full adjustment models.
Keywords: vascular access; central venous catheter; arteriovenous fistula; dialysis; vascular surgery vascular access; central venous catheter; arteriovenous fistula; dialysis; vascular surgery

Share and Cite

MDPI and ACS Style

Russu, E.; Bartus, R.; Florea, E.; Mureșan, A.; Bândea, P.; Mateica, P.; Tofana, I.G.; Ciucanu, C.C.; Arbănași, E.-M.; Ion, A.P.; et al. Dialysis on the Central Venous Catheter at the Time of Arteriovenous Fistula Creation Is Associated with Long-Term Vascular Access Failure. J. Clin. Med. 2026, 15, 3819. https://doi.org/10.3390/jcm15103819

AMA Style

Russu E, Bartus R, Florea E, Mureșan A, Bândea P, Mateica P, Tofana IG, Ciucanu CC, Arbănași E-M, Ion AP, et al. Dialysis on the Central Venous Catheter at the Time of Arteriovenous Fistula Creation Is Associated with Long-Term Vascular Access Failure. Journal of Clinical Medicine. 2026; 15(10):3819. https://doi.org/10.3390/jcm15103819

Chicago/Turabian Style

Russu, Eliza, Réka Bartus, Elena Florea, Alexandru Mureșan, Paula Bândea, Paul Mateica, Ionela Georgiana Tofana, Constantin Claudiu Ciucanu, Eliza-Mihaela Arbănași, Alexandru Petru Ion, and et al. 2026. "Dialysis on the Central Venous Catheter at the Time of Arteriovenous Fistula Creation Is Associated with Long-Term Vascular Access Failure" Journal of Clinical Medicine 15, no. 10: 3819. https://doi.org/10.3390/jcm15103819

APA Style

Russu, E., Bartus, R., Florea, E., Mureșan, A., Bândea, P., Mateica, P., Tofana, I. G., Ciucanu, C. C., Arbănași, E.-M., Ion, A. P., Chirilă, P., Hosu, I., Gliga, M. L., Mureșan, A. V., & Arbănași, E.-M. (2026). Dialysis on the Central Venous Catheter at the Time of Arteriovenous Fistula Creation Is Associated with Long-Term Vascular Access Failure. Journal of Clinical Medicine, 15(10), 3819. https://doi.org/10.3390/jcm15103819

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

Article Metrics

Back to TopTop