A Novel, Drinkable Food Supplement Formulation Reduces Hair Shedding and Increases the Percentage of Anagen Scalp Hair Follicles in Females with Hair Loss
Abstract
1. Introduction
2. Materials and Methods
2.1. Study Design and Population
2.2. Test Product
2.3. Study Endpoints and Procedures
2.4. Statistical Analysis
3. Results
3.1. The Tested Drinkable Food Supplement Significantly Increases the Percentage of Hair Follicles in the Anagen Phase
3.2. The Tested Food Supplement Increases Hair Density over Time
3.3. Self-Perception Questionnaire Data Reflect Perceived Hair Health Benefits
3.4. Hair Shedding Significantly Decreases After 6 Months, Indicating Reduced TE
3.5. Safety
4. Discussion
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
Abbreviations
| A:C/T | Anagen to Catagen-Telogen ratio |
| FPHL | Female Pattern Hair Loss |
| HF | Hair Follicle |
| LMM | Linear Mixed-effects Model |
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| All (n = 33) | |
|---|---|
| Mean age (SD), years | 32.05 (8.16) |
| Age range, years | 20–45 |
| Ethnicity, n (%) | |
| Caucasian | 33 (100%) |
| Hair type, n (%) | |
| Type 1 | 20 (60.6%) |
| Type 2 | 10 (30.3%) |
| Type 3 | 3 (9.1%) |
| Type 4 | - |
| Inclusion Criteria | Exclusion Criteria |
|---|---|
|
|
| Absolute no. of Hairs (Average, SD) | LMM * p-Values | |
|---|---|---|
| T0 | 191.13 (41.55) | - |
| T1 | 198.91 (41.72) | p < 0.01 |
| T2 | 205.42 (39.65) | p < 0.001 |
| T3 | 214.53 (41.26) | p < 0.001 |
| Percentage of Subjects (%) * | Self-Perception Results |
|---|---|
| 94% | Healthier hair |
| 94% | Stronger hair |
| 85% | Overall hair volume |
| 94% | Shinier hair |
| 91% | Overall decrease in hair shedding |
| 97% | Re-densifying effect satisfaction |
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Sáez Moya, M.; Westgate, G.E.; Paus, R.; Grohmann, D. A Novel, Drinkable Food Supplement Formulation Reduces Hair Shedding and Increases the Percentage of Anagen Scalp Hair Follicles in Females with Hair Loss. J. Clin. Med. 2025, 14, 8471. https://doi.org/10.3390/jcm14238471
Sáez Moya M, Westgate GE, Paus R, Grohmann D. A Novel, Drinkable Food Supplement Formulation Reduces Hair Shedding and Increases the Percentage of Anagen Scalp Hair Follicles in Females with Hair Loss. Journal of Clinical Medicine. 2025; 14(23):8471. https://doi.org/10.3390/jcm14238471
Chicago/Turabian StyleSáez Moya, Manuel, Gillian E. Westgate, Ralf Paus, and Daniela Grohmann. 2025. "A Novel, Drinkable Food Supplement Formulation Reduces Hair Shedding and Increases the Percentage of Anagen Scalp Hair Follicles in Females with Hair Loss" Journal of Clinical Medicine 14, no. 23: 8471. https://doi.org/10.3390/jcm14238471
APA StyleSáez Moya, M., Westgate, G. E., Paus, R., & Grohmann, D. (2025). A Novel, Drinkable Food Supplement Formulation Reduces Hair Shedding and Increases the Percentage of Anagen Scalp Hair Follicles in Females with Hair Loss. Journal of Clinical Medicine, 14(23), 8471. https://doi.org/10.3390/jcm14238471

