Predictive Value of Serial Model of End-Stage Liver Disease Score Determination in Patients with Postcardiotomy Extracorporeal Membrane Oxygenation
Abstract
1. Introduction
2. Materials and Methods
3. Results
3.1. Patient Characteristics and Laboratory Markers
3.2. Model of End-Stage Liver Disease Scores
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Variables | Total Cohort (n = 112) |
---|---|
Patient characteristics | |
Age [years] | 69 [61.7–74.7] |
Male [n (%)] | 81 (72.3) |
BMI [kg/m2] | 28 [24.9–31.0] |
Comorbidities, n (%) | |
CNS (Stroke/TIA) | 5 (4.5) |
Hypertension | 99 (88.4) |
CAD | 81 (72.3) |
STEMI | 6 (5.4) |
NSTEMI | 22 (19.6) |
Congestive heart failure | 81 (72.3) |
Diabetes | 36 (32.1) |
COPD | 23 (20.5) |
Cancer | 1 (0.9) |
Previous cardiac surgery | 20 (17.9) |
Log. EuroSCORE (patients n = 109; n = 3 missing data) | 7.15 [0.88–71.82] |
SAVEscore | −9 [−15.0–−5.0] |
ECMO indication, n (%) | |
CPB weaning failure, elective surgery | 33 (29.5) |
CPB weaning failure, urgent surgery | 26 (23.2) |
Postop. LCOS, elective surgery | 35 (31.3) |
Postop. LCOS, urgent surgery | 18 (16.1) |
Re-operation within 96 h of ECMO initiation, n (%) | |
No re-operation | 44 (39.3) |
Bleeding or cardiac tamponade | 45 (40.2) |
Cardiac bypass revision | 8 (7.1) |
Revision of femoral cannulation | 7 (6.3) |
Laparotomy | 7 (6.3) |
ECMO revision | 1 (0.9) |
Re-operation time, n (%) | |
No re-operation | 44 (39.3) |
Within 24 h of ECMO initiation | 55 (49.1) |
Within 24–48 h of ECMO initiation | 4 (3.6) |
More than 48 h after ECMO initiation | 9 (8.0) |
Hospital Admission | ECMO Initiation | 24 h after ECMO Initiation | 48 h after ECMO Initiation | 72 h after ECMO Initiation | 96 h after ECMO Initiation | |
---|---|---|---|---|---|---|
Bilirubin (µmol/L) | 14 [9.0–18.0] | 25 [15.0–37.8] | 34 [16.0–61.5] | 37 [15.0–78.5] | 38 [15.5–80.0] | 38 [14.5–73.8] |
Creatinine (µmol/L) | 90 [74.5–127.0] | 109 [82.0–142.5] | 138 [96.8–186.5] | 136 [88.0–172.0] | 144 [97.5–189.0] | 132 [100.0–194.0] |
GFR | 72.8 [47.61–97.16] | 65.4 [47.11–84.31] | 50.6 [37.67–76.36] | 50.7 [36.83–83.60] | 51.5 [35.92–74.75] | 50.5 [35.46–74.96] |
INR | 1.1 [1.00–1.30] | 1.6 [1.40–1.90] | 1.5 [1.2–1.7] | 1.3 [1.1–1.58] | 1.2 [1.10–1.40] | 1.2 [1.10–1.30] |
MELD | 10 [7.0–14.8] | 17 [13.0–24.8} | 20 [15.0–28.0] | 22 [12.0–28.8] | 17 [12.0–22.0] | 16 [12.0–21.0] |
CTP | 6 [5.0–7.0] | 7 [6.0–8.0] | 7 [6.0–8.0] | 7 [6.0–8.0] | 6 [5.0–7.0] | 6 [5.0–7.0] |
ECMO flow [L/m2] | - | 2.5 [2.17–2.75] | 2.5 [2.25–2.79] | 2.5 [2.18–2.77] | 2.5 [2.01–2.79] | 2.4 [1.81–2.87] |
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Sommerfeld, O.; Neumann, C.; Pfeifer, M.-D.; Faerber, G.; Kirov, H.; von Loeffelholz, C.; Doenst, T.; Sponholz, C. Predictive Value of Serial Model of End-Stage Liver Disease Score Determination in Patients with Postcardiotomy Extracorporeal Membrane Oxygenation. J. Clin. Med. 2024, 13, 1856. https://doi.org/10.3390/jcm13071856
Sommerfeld O, Neumann C, Pfeifer M-D, Faerber G, Kirov H, von Loeffelholz C, Doenst T, Sponholz C. Predictive Value of Serial Model of End-Stage Liver Disease Score Determination in Patients with Postcardiotomy Extracorporeal Membrane Oxygenation. Journal of Clinical Medicine. 2024; 13(7):1856. https://doi.org/10.3390/jcm13071856
Chicago/Turabian StyleSommerfeld, Oliver, Caroline Neumann, Marcel-Dominic Pfeifer, Gloria Faerber, Hristo Kirov, Christian von Loeffelholz, Torsten Doenst, and Christoph Sponholz. 2024. "Predictive Value of Serial Model of End-Stage Liver Disease Score Determination in Patients with Postcardiotomy Extracorporeal Membrane Oxygenation" Journal of Clinical Medicine 13, no. 7: 1856. https://doi.org/10.3390/jcm13071856
APA StyleSommerfeld, O., Neumann, C., Pfeifer, M.-D., Faerber, G., Kirov, H., von Loeffelholz, C., Doenst, T., & Sponholz, C. (2024). Predictive Value of Serial Model of End-Stage Liver Disease Score Determination in Patients with Postcardiotomy Extracorporeal Membrane Oxygenation. Journal of Clinical Medicine, 13(7), 1856. https://doi.org/10.3390/jcm13071856