Next Article in Journal
Associations between Kidney Disease Progression and Metabolomic Profiling in Stable Kidney Transplant Recipients—A 3 Year Follow-Up Prospective Study
Next Article in Special Issue
The Role of Psychological Variables in Predicting Rehabilitation Outcomes After Spinal Cord Injury: An Artificial Neural Networks Study
Previous Article in Journal
Impact of Inhaled Nitric Oxide (iNO) on the Outcome of COVID-19 Associated ARDS
Previous Article in Special Issue
Nociception Coma Scale—Revised with Personalized Painful Stimulus Versus Standard Stimulation in Persons with Disorders of Consciousness: An International Multicenter Study
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
JCM
Volume 13
Issue 19
10.3390/jcm13195982
jcm-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Article

Quality-of-Life- and Cognitive-Oriented Rehabilitation Program through NeuronUP in Older People with Alzheimer’s Disease: A Randomized Clinical Trial

by
Anthia Cristina Fabara-Rodríguez
1,
Cristina García-Bravo
2,3,*,
Sara García-Bravo
3,4,
Isabel Quirosa-Galán
5,
Mª Pilar Rodríguez-Pérez
4,
Jorge Pérez-Corrales
2,
Gemma Fernández-Gómez
5,6,
Madeleine Donovan
7 and
Elisabet Huertas-Hoyas
4
1
Geriasa Brunete, Nursing Home, 28690 Brunete, Spain
2
Department of Physical Therapy, Occupational Therapy, Physical Medicine and Rehabilitation, Research Group of Humanities and Qualitative Research in Health Science (Hum&QRinHS), 28922 Alcorcón, Spain
3
Physiocare Madrid, Physiotherapy Clinic, 28026 Madrid, Spain
4
Department of Physical Therapy, Occupational Therapy, Physical Medicine and Rehabilitation, Universidad Rey Juan Carlos, 28922 Alcorcón, Spain
5
PhD Program in Health Sciences, Universidad Rey Juan Carlos, 28922 Alcorcón, Spain
6
TANGRAM, Center for Comprehensive Care for Children and Adolescents, 28032 Madrid, Spain
7
Independent Researcher, 13409 Berlin, Germany
*
Author to whom correspondence should be addressed.
J. Clin. Med. 2024, 13(19), 5982; https://doi.org/10.3390/jcm13195982
Submission received: 14 August 2024 / Revised: 18 September 2024 / Accepted: 7 October 2024 / Published: 8 October 2024
(This article belongs to the Special Issue Increasing the Efficacy of Neurorehabilitation: From the Translationality of Technology to Personalized Rehabilitation Medicine)
Browse Figures
Versions Notes

Abstract

(1) Background: Alzheimer’s disease (AD) is a progressive neurodegenerative disorder marked by cognitive decline and functional impairment. The NeuronUP platform is a computer program whose main function is cognitive stimulation through three types of activities that change so that the user does not manage to learn it. This program provides opportunities to work on various domains, including activities of daily living (ADLs), social skills, and cognitive functions. The main objective of this randomized clinical trial was to assess the impact of integrating the NeuronUP platform with conventional occupational therapy to enhance or maintain cognitive, perceptual, and quality of life (QoL) abilities in people with AD compared to a control group. (2) Methods: A randomized, single-blind clinical trial was conducted. The sample was randomized using a software program, OxMar, which allowed the separation of the sample into a control group (CG) that received their conventional occupational therapy sessions and an experimental group (EG) that received therapy with NeuronUP, in addition to their conventional occupational therapy sessions. An eighteen-week intervention was conducted. (3) Results: The study included 20 participants, and significant differences were observed in most variables analyzed, indicating improvements after the intervention, particularly in measures of QoL and cognitive status. (4) Conclusions: Our findings demonstrate that an eighteen-week experimental protocol, incorporating the NeuronUP platform alongside conventional occupational therapy, led to improvements in cognitive status and QoL in older adults with AD. Thus, integrating the NeuronUP platform as a complementary tool to occupational therapy can be a valuable resource for enhancing the QoL of individuals with AD. However, due to the small sample size, further studies are needed to corroborate these findings.
Keywords: Alzheimer’s disease; occupational therapy; rehabilitation; NeuronUP; quality of life; cognitive stimulation Alzheimer’s disease; occupational therapy; rehabilitation; NeuronUP; quality of life; cognitive stimulation

Share and Cite

MDPI and ACS Style

Fabara-Rodríguez, A.C.; García-Bravo, C.; García-Bravo, S.; Quirosa-Galán, I.; Rodríguez-Pérez, M.P.; Pérez-Corrales, J.; Fernández-Gómez, G.; Donovan, M.; Huertas-Hoyas, E. Quality-of-Life- and Cognitive-Oriented Rehabilitation Program through NeuronUP in Older People with Alzheimer’s Disease: A Randomized Clinical Trial. J. Clin. Med. 2024, 13, 5982. https://doi.org/10.3390/jcm13195982

AMA Style

Fabara-Rodríguez AC, García-Bravo C, García-Bravo S, Quirosa-Galán I, Rodríguez-Pérez MP, Pérez-Corrales J, Fernández-Gómez G, Donovan M, Huertas-Hoyas E. Quality-of-Life- and Cognitive-Oriented Rehabilitation Program through NeuronUP in Older People with Alzheimer’s Disease: A Randomized Clinical Trial. Journal of Clinical Medicine. 2024; 13(19):5982. https://doi.org/10.3390/jcm13195982

Chicago/Turabian Style

Fabara-Rodríguez, Anthia Cristina, Cristina García-Bravo, Sara García-Bravo, Isabel Quirosa-Galán, Mª Pilar Rodríguez-Pérez, Jorge Pérez-Corrales, Gemma Fernández-Gómez, Madeleine Donovan, and Elisabet Huertas-Hoyas. 2024. "Quality-of-Life- and Cognitive-Oriented Rehabilitation Program through NeuronUP in Older People with Alzheimer’s Disease: A Randomized Clinical Trial" Journal of Clinical Medicine 13, no. 19: 5982. https://doi.org/10.3390/jcm13195982

APA Style

Fabara-Rodríguez, A. C., García-Bravo, C., García-Bravo, S., Quirosa-Galán, I., Rodríguez-Pérez, M. P., Pérez-Corrales, J., Fernández-Gómez, G., Donovan, M., & Huertas-Hoyas, E. (2024). Quality-of-Life- and Cognitive-Oriented Rehabilitation Program through NeuronUP in Older People with Alzheimer’s Disease: A Randomized Clinical Trial. Journal of Clinical Medicine, 13(19), 5982. https://doi.org/10.3390/jcm13195982

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

Article Metrics

Back to TopTop