Left Ventricular “Longitudinal Rotation” and Conduction Abnormalities—A New Outlook on Dyssynchrony
Abstract
:1. Introduction
2. Methods
2.1. Patient Selection
2.2. Echocardiography
2.3. Longitudinal Rotation Quantification
2.4. Statistical Analysis
3. Results
3.1. Clinical and Echocardiographic Data
3.2. Longitudinal Rotation
4. Discussion
4.1. Main Findings
4.2. Longitudinal Rotation
4.3. Clinical Outlook
4.4. Limitations
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Normal (n = 19) | LBBB (n = 21) | p Value (LBBB vs. Normal) | RBBB (n = 20) | p Value (RBBB vs. Normal) | p Value (LBBB vs. RBBB) | |
---|---|---|---|---|---|---|
Age | 61 ± 14 | 67 ± 12 | 0.0497 | 71 ± 13 | 0.008 | 0.16 |
Female gender n, % | 6 (31.6) | 7 (33.3) | 0.9 | 5 (25) | 0.65 | 0.56 |
QRS duration (ms) | 95 ± 8 | 159 ± 15 | 0.00001 | 141 ± 11 | 0.00001 | 0.00001 |
Heart rate (min−1) | 70 ± 12 | 78 ± 21 | 0.17 | 75 ± 13 | 0.24 | 0.56 |
Ejection fraction (%) | 62 ± 6 | 45 ± 17 | 0.0001 | 55 ± 14 | 0.038 | 0.043 |
LVEDD (mm) | 53 ± 4 | 61 ± 12 | 0.004 | 54 ± 10 | 0.2 | 0.04 |
LVESD (mm) | 34 ± 5 | 47 ± 14 | 0.0002 | 38 ± 12 | 0.06 | 0.02 |
Severe valvular disease n, % | 1 (5.3) | 5 (23.8) | 0.1 | 6 (30) | 0.1 | 0.9 |
Regional WMA n, % | 2 (10.5) | 8 (38.1) | 0.044 | 7 (35) | 0.07 | 0.8 |
CHF n, % | 1 (5.3) | 14 (66.7) | 0.00006 | 6 (30) | 0.044 | 0.02 |
Clockwise rotation n, % | 11 (58) | 21 (100) | <0.005 | 7 (35) | 0.15 | <0.0005 |
Longitudinal rotation angle (°) | −1.4 ± 3 | −3.9 ± 2.4 | 0.005 | 0.1 ± 2.2 | 0.093 | 0.00001 |
Time to peak rotation (ms) | 395 ± 98 | 339 ± 135 | 0.1447 | 367 ± 89 | 0.356 | 0.437 |
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Marai, I.; Haddad, R.; Andria, N.; Kinany, W.; Hazanov, Y.; Kleinberg, B.M.; Birati, E.; Carasso, S. Left Ventricular “Longitudinal Rotation” and Conduction Abnormalities—A New Outlook on Dyssynchrony. J. Clin. Med. 2023, 12, 745. https://doi.org/10.3390/jcm12030745
Marai I, Haddad R, Andria N, Kinany W, Hazanov Y, Kleinberg BM, Birati E, Carasso S. Left Ventricular “Longitudinal Rotation” and Conduction Abnormalities—A New Outlook on Dyssynchrony. Journal of Clinical Medicine. 2023; 12(3):745. https://doi.org/10.3390/jcm12030745
Chicago/Turabian StyleMarai, Ibrahim, Rabea Haddad, Nizar Andria, Wadi Kinany, Yevgeni Hazanov, Bruce M. Kleinberg, Edo Birati, and Shemy Carasso. 2023. "Left Ventricular “Longitudinal Rotation” and Conduction Abnormalities—A New Outlook on Dyssynchrony" Journal of Clinical Medicine 12, no. 3: 745. https://doi.org/10.3390/jcm12030745
APA StyleMarai, I., Haddad, R., Andria, N., Kinany, W., Hazanov, Y., Kleinberg, B. M., Birati, E., & Carasso, S. (2023). Left Ventricular “Longitudinal Rotation” and Conduction Abnormalities—A New Outlook on Dyssynchrony. Journal of Clinical Medicine, 12(3), 745. https://doi.org/10.3390/jcm12030745