Years of Potential Life Lost on Renal Replacement Therapy: Retrospective Study Cohort
Abstract
:1. Introduction
2. Materials and Methods
3. Results
3.1. Kidney Transplantation
3.2. Years of Potential Life Lost
3.3. YPLL Kidney Transplantation Versus Dialysis
4. Discussion
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Conflicts of Interest
References
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N = 11,551 | Renal Transplantation N = 3776 | No Renal Transplantation N = 7775 | p Value | ||||
---|---|---|---|---|---|---|---|
Min–Max | Mean (SD) | 95% CI | Min–Max | Mean (SD) | 95% CI | ||
Age (years) | 15–80 | 51 (13.5) | (50.6; 51.5) | 15–94 | 68.3 (12.6) | (68.0; 68.6) | <0.001 |
Sex | |||||||
Women N (%) | 1371 (36.3) | (34.8; 37.9) | 2922 (37.6) | (36.5; 38.7) | 0.184 | ||
Men N (%) | 2405 (63.7) | (62.1; 65.2) | 4853 (62.4) | (61.3; 63.5) | |||
Charlson index | 2–13 | 3.8 (1.8) | (3.8; 3.9) | 2–20 | 7.0 (2.4) | (7.0; 7.1) | <0.001 |
Vital status | |||||||
Alive N (%) | 3413 (90.4) | (89.4; 91.3) | 3238 (41.6) | (40.6; 42.7) | <0.001 | ||
Dead N (%) | 363 (9.6) | (8.7; 10.6) | 4537 (58.4) | (57.3; 59.4) | |||
Age at death * (Years) | 15–84 | 65.4 (10.2) | (64.3; 66.5) | 19–98 | 73.3 (11.1) | (73.0; 73.6) | <0.001 |
MEN | WOMEN | |||||
---|---|---|---|---|---|---|
Age Onset RRT | Total YPLL | N Patient | YPLL/ Patient | Total YPLL | N Patient | YPLL/ Patient |
15–29 years | 390.3 | 218 | 1.79 | 486.6 | 166 | 2.93 |
30–34 years | 743.2 | 191 | 3.89 | 575.7 | 94 | 6.12 |
35–39 years | 904.3 | 227 | 3.98 | 567.0 | 129 | 4.40 |
40–44 years | 1689.5 | 336 | 5.03 | 1053.9 | 196 | 5.38 |
45–49 years | 3274.2 | 485 | 6.75 | 1117.1 | 257 | 4.35 |
50–54 years | 4517.8 | 566 | 7.98 | 2039.9 | 308 | 6.62 |
55–59 years | 5450.6 | 698 | 7.81 | 3096.9 | 373 | 8.30 |
60–64 years | 6675.9 | 832 | 8.02 | 3981.9 | 450 | 8.85 |
65–69 years | 7762.8 | 954 | 8.14 | 4471.0 | 511 | 8.75 |
70–74 years | 7181.8 | 1027 | 6.99 | 4919.0 | 593 | 8.30 |
75–79 years | 5775.4 | 943 | 6.12 | 4694.5 | 683 | 6.87 |
80–84 years | 3025.3 | 619 | 4.89 | 2296.9 | 404 | 5.69 |
85–89 years | 567.1 | 147 | 3.86 | 495.2 | 121 | 4.09 |
90 years and older | 51.9 | 15 | 3.46 | 25.7 | 8 | 3.21 |
Total | 48,010.1 | 7258 | 6.61 | 29,821.2 | 4293 | 6.95 |
MEN | WOMEN | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Dialysis | Renal Transplantation | Dialysis | Renal Transplantation | |||||||||
Age Onset RRT | Total YPLL | N Patient | YPLL/ Patient | Total YPLL | N Patient | YPLL/ Patient | Total YPLL | N Patient | YPLL/ Patient | Total YPLL | N Patient | YPLL/ Patient |
15–29 years | 325.7 | 52 | 6.3 | 64.5 | 166 | 0.4 | 423.7 | 37 | 11.5 | 62.8 | 129 | 0.5 |
30–34 years | 696.6 | 54 | 12.9 | 46.6 | 137 | 0.3 | 470.8 | 24 | 19.6 | 104.9 | 70 | 1.5 |
35–39 years | 657.6 | 52 | 12.6 | 246.7 | 175 | 1.4 | 423.4 | 33 | 12.8 | 143.6 | 96 | 1.5 |
40–44 years | 1245.0 | 113 | 11.0 | 444.5 | 223 | 2.0 | 844.9 | 55 | 15.4 | 209.0 | 141 | 1.5 |
45–49 years | 2766.9 | 177 | 15.6 | 507.3 | 308 | 1.6 | 966.7 | 80 | 12.1 | 150.4 | 177 | 0.8 |
50–54 years | 3898.0 | 263 | 14.8 | 619.8 | 303 | 2.0 | 1644.4 | 118 | 13.9 | 395.5 | 190 | 2.1 |
55–59 years | 4425.1 | 360 | 12.3 | 1025.5 | 338 | 3.0 | 2734.7 | 200 | 13.7 | 362.2 | 173 | 2.1 |
60–64 years | 5814.7 | 519 | 11.2 | 861.2 | 313 | 2.8 | 3240.5 | 278 | 11.7 | 741.4 | 172 | 4.3 |
65–69 years | 6713.2 | 680 | 9.9 | 1049.6 | 274 | 3.8 | 3936.7 | 370 | 10.6 | 534.3 | 141 | 3.8 |
70–74 years | 6799.1 | 888 | 7.7 | 382.7 | 139 | 2.8 | 4632.3 | 523 | 8.9 | 286.7 | 70 | 4.1 |
75–79 years | 5743.2 | 916 | 6.3 | 32.2 | 27 | 1.2 | 4659.9 | 671 | 6.9 | 34.6 | 12 | 2.9 |
80–84 years | 3025.3 | 617 | 4.9 | 0.0 | 2 | 0.0 | 2296.9 | 404 | 5.7 | 0.0 | 0 | 0.0 |
85–89 years | 567.1 | 147 | 3.9 | 0.0 | 0 | 0.0 | 495.2 | 121 | 4.1 | 0.0 | 0 | 0.0 |
90 years and older | 51.9 | 15 | 3.5 | 0.0 | 0 | 0.0 | 25.7 | 8 | 3.2 | 0.0 | 0 | 0.0 |
Total | 42,794.0 | 4853 | 8.8 | 5280.6 | 2405 | 2.2 | 26,795.7 | 2922 | 9.2 | 3025.5 | 1371 | 2.2 |
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Muñoz-Terol, J.M.; Rocha, J.L.; Castro-de la Nuez, P.; García-Cabrera, E.; Vilches-Arenas, Á. Years of Potential Life Lost on Renal Replacement Therapy: Retrospective Study Cohort. J. Clin. Med. 2023, 12, 51. https://doi.org/10.3390/jcm12010051
Muñoz-Terol JM, Rocha JL, Castro-de la Nuez P, García-Cabrera E, Vilches-Arenas Á. Years of Potential Life Lost on Renal Replacement Therapy: Retrospective Study Cohort. Journal of Clinical Medicine. 2023; 12(1):51. https://doi.org/10.3390/jcm12010051
Chicago/Turabian StyleMuñoz-Terol, José Manuel, José L. Rocha, Pablo Castro-de la Nuez, Emilio García-Cabrera, and Ángel Vilches-Arenas. 2023. "Years of Potential Life Lost on Renal Replacement Therapy: Retrospective Study Cohort" Journal of Clinical Medicine 12, no. 1: 51. https://doi.org/10.3390/jcm12010051
APA StyleMuñoz-Terol, J. M., Rocha, J. L., Castro-de la Nuez, P., García-Cabrera, E., & Vilches-Arenas, Á. (2023). Years of Potential Life Lost on Renal Replacement Therapy: Retrospective Study Cohort. Journal of Clinical Medicine, 12(1), 51. https://doi.org/10.3390/jcm12010051