Microbiologic Analysis of Removed Silicone Punctal Plugs in Dry Eye Patients
Abstract
1. Introduction
2. Materials and Methods
3. Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Values | |
---|---|
Number of patients (eyes) | 58 (64) |
Age (years) | 57.03 ± 12.9 (23–84) |
Gender | |
Male | 19 (32.8) |
Female | 39 (67.2) |
Laterality | |
OD | 30 (46.9) |
OS | 34 (53.1) |
Sjögren’s syndrome | 9 (15.5) |
Diabetes mellitus | 6 (10.3) |
Hypertension | 6 (10.3) |
Comorbid anterior segment diseases | 9 (15.5) |
Avellino corneal dystrophy | 1 (1.7) |
Diabetic keratopathy | 1 (1.7) |
Exposure keratopathy | 1 (1.7) |
Herpes keratitis | 1 (1.7) |
Infectious scleritis | 1 (1.7) |
Keratoconus | 1 (1.7) |
Nodular episcleritis | 1 (1.7) |
Salzmann nodular degeneration | 1 (1.7) |
Scleromalacia | 1 (1.7) |
Number of Isolates (%) | A (%) | B (%) | p Value | |
---|---|---|---|---|
Protrusion without granuloma | 21 (32.8) | 12 (27.9) | 9 (42.9) | 0.232 * |
Protrusion with granuloma | 19 (29.7) | 15 (34.9) | 4 (19.0) | 0.193 * |
Inflammation | 14 (21.9) | 10 (23.3) | 4 (19.0) | 0.755 † |
Epiphora | 9 (14.0) | 5 (11.6) | 4 (19.0) | 0.329 † |
Foreign body sensation | 1 (1.6) | 1 (2.3) | 0 | 1.000 † |
Total | 64 (100) | 43 (100) | 21 (100) |
Values | |
---|---|
Duration of plug retention (months) | 7.04 ± 5.7 (0.25–20) |
Plug location | |
Upper | 14 (21.9) |
Lower | 50 (78.1) |
Kinds of plugs | |
SuperEagle Plug™ | 43 (67.2) |
Parasol Punctum Plug™ | 21 (32.8) |
Positive culture results | 27 (42.2) |
Gram stain | |
Gram (+) | 12 (18.8) |
Gram (−) | 15 (23.4) |
Number of Isolates (%) | A (%) | B (%) | p Value † | |
---|---|---|---|---|
Gram (+) cocci | ||||
Staphylococcus epidermidis | 4 (14.8) | 4 (19.0) | 0 | 0.545 |
Staphylococcus aureus | 1 (3.7) | 1 (4.8) | 0 | 1.000 |
Streptococcus mitis | 1 (3.7) | 1 (4.8) | 0 | 1.000 |
Enterococcus faecalis | 1 (3.7) | 1 (4.8) | 0 | 1.000 |
Gram (+) rod | ||||
Bacillus simplex | 1 (3.7) | 0 | 1 (16.7) | 0.222 |
Corynebacterium kroppensteditii | 1 (3.7) | 1 (4.8) | 0 | 1.000 |
Corynebacterium propinquum | 1 (3.7) | 1 (4.8) | 0 | 1.000 |
Corynebacterium bovis | 1 (3.7) | 1 (4.8) | 0 | 1.000 |
Corynebacterium macginleyi | 1 (3.7) | 0 | 1 (16.7) | 0.222 |
Gram (−) rod | ||||
Klebsiella aerogenes | 5 (18.5) | 4 (19.0) | 1 (16.7) | 1.000 |
Pseudomonas aeruginosa | 4 (14.8) | 4 (19.0) | 0 | 0.545 |
Citrobacter koseri | 2 (7.4) | 1 (4.8) | 1 (16.7) | 0.402 |
Acinetobacter species | 1 (3.7) | 1 (4.8) | 0 | 1.000 |
Enterobacter species | 1 (3.7) | 0 | 1 (16.7) | 0.222 |
Pantoea agglomerans | 1 (3.7) | 0 | 1 (16.7) | 0.222 |
Stenotrophomonas maltophilia | 1 (3.7) | 1 (4.8) | 0 | 1.000 |
Total | 27 (100) | 21 (100) | 6 (100) |
Antibiotics | Specimen (n) | Susceptible (n) | Susceptibility (%) |
---|---|---|---|
Fluoroquinolone | 45 | 33 | 73.3 |
Ciprofloxacin | 20 | 15 | 75.0 |
Levofloxacin | 21 | 17 | 81.0 |
Moxifloxacin | 4 | 1 | 25.0 |
Vancomycin | 6 | 6 | 100.0 |
Cephalosporin | |||
2nd generation | 22 | 12 | 54.5 |
Cefuroxime | 13 | 9 | 69.2 |
Cefoxitin | 9 | 3 | 33.3 |
3rd generation | 26 | 23 | 88.5 |
Ceftazidime | 15 | 14 | 93.3 |
Cefotaxime | 11 | 9 | 81.8 |
4th generation | 18 | 13 | 72.2 |
Cefepime | 18 | 13 | 72.2 |
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Jung, I.; Yoon, J.S.; Ko, B.Y. Microbiologic Analysis of Removed Silicone Punctal Plugs in Dry Eye Patients. J. Clin. Med. 2022, 11, 2326. https://doi.org/10.3390/jcm11092326
Jung I, Yoon JS, Ko BY. Microbiologic Analysis of Removed Silicone Punctal Plugs in Dry Eye Patients. Journal of Clinical Medicine. 2022; 11(9):2326. https://doi.org/10.3390/jcm11092326
Chicago/Turabian StyleJung, Il, Jung Suk Yoon, and Byung Yi Ko. 2022. "Microbiologic Analysis of Removed Silicone Punctal Plugs in Dry Eye Patients" Journal of Clinical Medicine 11, no. 9: 2326. https://doi.org/10.3390/jcm11092326
APA StyleJung, I., Yoon, J. S., & Ko, B. Y. (2022). Microbiologic Analysis of Removed Silicone Punctal Plugs in Dry Eye Patients. Journal of Clinical Medicine, 11(9), 2326. https://doi.org/10.3390/jcm11092326