Next Article in Journal
The Feasibility of Surface Electromyography in Monitoring Orbicularis Oculi Recovery after Anterior Approach Levator Aponeurosis Advancement
Next Article in Special Issue
Anterior Pedicled Nasal Flap in Frontal Sinus Drill-Out Patients: A Randomised Controlled Pilot Study
Previous Article in Journal
Exploring Renal Changes after Bariatric Surgery in Patients with Severe Obesity
 
 
Article

Autologous Fat Plus Platelet-Rich Plasma versus Autologous Fat Alone on Sulcus Vocalis

1
Department of Otolaryngology-Head and Neck Surgery, China Medical University Hospital, Taichung 40402, Taiwan
2
School of Medicine, China Medical University, Taichung 40402, Taiwan
3
Department of Otolaryngology Head and Neck Surgery, Asia University Hospital, Taichung 40402, Taiwan
4
Department of Audiology and Speech-Language Pathology, Asia University, Taichung 41354, Taiwan
5
Graduate Institute of Biomedical Sciences, China Medical University, Taichung 40402, Taiwan
6
Department of Sport Performance, National Taiwan University of Sport, Taichung 404401, Taiwan
*
Author to whom correspondence should be addressed.
Academic Editors: Eng Ooi and Renee Speyer
J. Clin. Med. 2022, 11(3), 725; https://doi.org/10.3390/jcm11030725
Received: 25 December 2021 / Revised: 22 January 2022 / Accepted: 27 January 2022 / Published: 29 January 2022
Sulcus vocalis is a frequent cause of glottic insufficiency that leads to incomplete vocal fold closure during phonation. Type II sulcus vocalis is defined as a partial defect of the lamina propria (LP). Treatment with fillers, such as fat or hyaluronic acid (HA), in the vocal folds is widely used, but the duration of effect is variable. Platelet-rich plasma (PRP) can enhance the survival of autologous fat in fat grafting, and also is used to treat sulcus vocalis. This study aimed to compare the effectiveness of autologous fat graft versus fat graft plus PRP to treat type II sulcus vocalis. Thirty-four patients with a voice handicap index (VHI) ≥ 11 were randomized to two groups, which received LP injections of fat graft (n = 17) or fat graft plus PRP (n = 17). At 1 month and 6 months after injection, the VHI decreased significantly in both groups. The fat plus PRP group had better Jitter, Shimmer, and noise to harmonic ratio (NHR) in 1 month and 6 months after surgery. The fat plus PRP group resulted in lower VHI scores one month after surgery, and stroboscopy revealed sustained smaller gaps after six months. These results indicate that a combination of fat graft plus PRP is safe and effective for treating sulcus vocalis type II and associated vocal atrophy. View Full-Text
Keywords: sulcus vocalis; lamina propria; platelet-rich plasma; autologous fat sulcus vocalis; lamina propria; platelet-rich plasma; autologous fat
Show Figures

Figure 1

MDPI and ACS Style

Tsou, Y.-A.; Tien, V.H.-C.; Chen, S.-H.; Shih, L.-C.; Lin, T.-C.; Chiu, C.-J.; Chang, W.-D. Autologous Fat Plus Platelet-Rich Plasma versus Autologous Fat Alone on Sulcus Vocalis. J. Clin. Med. 2022, 11, 725. https://doi.org/10.3390/jcm11030725

AMA Style

Tsou Y-A, Tien VH-C, Chen S-H, Shih L-C, Lin T-C, Chiu C-J, Chang W-D. Autologous Fat Plus Platelet-Rich Plasma versus Autologous Fat Alone on Sulcus Vocalis. Journal of Clinical Medicine. 2022; 11(3):725. https://doi.org/10.3390/jcm11030725

Chicago/Turabian Style

Tsou, Yung-An, Vincent Hui-Chi Tien, Sheng-Hwa Chen, Liang-Chun Shih, Tzu-Chieh Lin, Chien-Jen Chiu, and Wen-Dien Chang. 2022. "Autologous Fat Plus Platelet-Rich Plasma versus Autologous Fat Alone on Sulcus Vocalis" Journal of Clinical Medicine 11, no. 3: 725. https://doi.org/10.3390/jcm11030725

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop