Multimorbidity and Polytherapy in Patients with Femoral Neck Fracture: A Retrospective Observational Study
Abstract
:1. Introduction
2. Materials and Methods
2.1. Measures
2.2. Statistical Analysis
3. Results
3.1. Demographic Data
3.2. Multimorbidity
3.3. Polytherapy
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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All Sample (n = 917) | |
---|---|
Sex, n (%) | |
Female | 706 (77.0) |
Male | 211 (23.0) |
Age (years), mean ± std | 84 ± 7.6 |
Age, n (%) | |
65–69 | 51 (5.6) |
70–74 | 74 (8.1) |
75–79 | 131 (14.3) |
80–84 | 187 (20.4) |
85–89 | 267 (29.1) |
90–94 | 168 (18.3) |
95–99 | 35 (3.8) |
>100 | 4 (0.4) |
Education, n (%) | |
No academic qualifications | 430 (46.9) |
Primary school diploma | 276 (30.1) |
Middle school graduation | 117 (12.8) |
High school graduation | 78 (8.5) |
University degree | 10 (1.1) |
Bachelor’s degree | 6 (0.7) |
All Sample (n = 917) | |
---|---|
Number of chronic conditions, n (%) | |
0 | 453 (49.4) |
1 | 280 (30.5) |
2 | 118 (12.9) |
3 | 48 (5.2) |
4 | 16 (1.7) |
6 | 2 (0.2) |
Number of drugs used, n (%) | |
0 | 19 (2.1) |
1–4 | 83 (9.0) |
5–9 | 317 (34.6) |
≥10 | 498 (54.3) |
Variable | OR (95%CI) | p-Value | |
---|---|---|---|
Multimorbidity (≥2 comorbid conditions) | Yes vs. No | 3.0 (1.4–6.3) | 0.004 |
LOS (days) | >9 vs. ≤9 | 1.8 (1.1–2.8) | 0.013 |
Variable | HR (95%CI) | p-Value | |
---|---|---|---|
Polytherapy (≥5 drugs) | Yes vs. No | 0.3 (0.2–0.5) | <0.0001 |
Multimorbidity (≥2 comorbid conditions) | Yes vs. No | 1.7 (1.2–2.4) | 0.003 |
Sex | M vs. F | 2.6 (1.9–3.5) | <0.0001 |
Age (years) | ≥85 vs. <85 | 2.9 (2.0–4.0) | <0.0001 |
LOS (days) | >9 vs. ≤9 | 1.1 (0.8–1.5) | 0.531 |
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Borsari, V.; Veronesi, F.; Carretta, E.; Fini, M. Multimorbidity and Polytherapy in Patients with Femoral Neck Fracture: A Retrospective Observational Study. J. Clin. Med. 2022, 11, 6405. https://doi.org/10.3390/jcm11216405
Borsari V, Veronesi F, Carretta E, Fini M. Multimorbidity and Polytherapy in Patients with Femoral Neck Fracture: A Retrospective Observational Study. Journal of Clinical Medicine. 2022; 11(21):6405. https://doi.org/10.3390/jcm11216405
Chicago/Turabian StyleBorsari, Veronica, Francesca Veronesi, Elisa Carretta, and Milena Fini. 2022. "Multimorbidity and Polytherapy in Patients with Femoral Neck Fracture: A Retrospective Observational Study" Journal of Clinical Medicine 11, no. 21: 6405. https://doi.org/10.3390/jcm11216405
APA StyleBorsari, V., Veronesi, F., Carretta, E., & Fini, M. (2022). Multimorbidity and Polytherapy in Patients with Femoral Neck Fracture: A Retrospective Observational Study. Journal of Clinical Medicine, 11(21), 6405. https://doi.org/10.3390/jcm11216405