What Does Bone Corticalization around Dental Implants Mean in Light of Ten Years of Follow-Up?

Round 1

Reviewer 1 Report

This study is a prospective study that attempts to analyze the clinical significance of peri-implant bone corticalization after functional loading. This study included 554 patients, and 1556 implants, with a significant follow-up period of 10 years of functional loading. 

Although an intriguing subject the manuscript has several issues that must be addressed.

Please see the enclosed PDF for further details.

Comments for author File: Comments.pdf

Author Response

Please, find the attached file with detailed reply.

Author Response File: Author Response.pdf

Reviewer 2 Report

Dear Authors,

thank you for your manuscript dealing with bone corticalization around dental implants. I think that your work is really interesting and with good scientific soundness. The radiologic documentation is very relevant.

Howver, the only issue in my opinion is related to the bibliography. I think that you should remove old references and add new ones. Moreover, it could be interesting to add in the discussion the influence of the treatment of peri-implant sites on the parameters evaluated by you. In particular, the administration of ozone represent a hot topic. You could for example refer to the following research.

Butera, A.; Gallo, S.; Pascadopoli, M.; Luraghi, G.; Scribante, A. Ozonized Water Administration in Peri-Implant Mucositis Sites: A Randomized Clinical Trial. Appl. Sci. 2021, 11, 7812. https://doi.org/10.3390/app11177812

Yours faithfully,

The Reviewer

Author Response

Please, find the attached file with detailed reply.

Author Response File: Author Response.pdf

Round 2

Reviewer 1 Report

The authors have improved the manuscript. 

Author Response

Thank you for your appreciation.

Best regards

Marcin Kozakiewicz

Reviewer 2 Report

Dear Authors,

congratulations for your work. You have addressed all the points suggested by me.

There is a last thing which I think could be still done to improve the quality of your manuscript which is, if possible, an improvement of the quality of figure 2.

Anyway the manuscript now deserves to be published in the journal.

Yours faithfully,

The Reviewer

Author Response

Dear Sir

Thank you for time and advises. I finally have improved fig. 2 and fig3 in the latest version of revision.