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Article

Hypoperfusion Index Ratio as a Surrogate of Collateral Scoring on CT Angiogram in Large Vessel Stroke

Department of Neurology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 704, Taiwan
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Authors to whom correspondence should be addressed.
Academic Editor: Hyo Suk Nam
J. Clin. Med. 2021, 10(6), 1296; https://doi.org/10.3390/jcm10061296
Received: 8 February 2021 / Revised: 17 March 2021 / Accepted: 18 March 2021 / Published: 21 March 2021
(This article belongs to the Special Issue Thrombolysis and Thrombectomy in Acute Ischemic Stroke)
Background: This study was to evaluate the correlation of the hypoperfusion intensity ratio (HIR) with the collateral score from multiphase computed tomography angiography (mCTA) among patients with large vessel stroke. Method: From February 2019 to May 2020, we retrospectively reviewed the patients with large vessel strokes (intracranial carotid artery or proximal middle cerebral artery occlusion). HIR was defined as a Tmax > 10 s lesion volume divided by a Tmax > 6 s lesion volume, which was calculated by automatic software (Syngo.via, Siemens). The correlation between the HIR and mCTA score was evaluated by Pearson’s correlation. The cutoff value predicting the mCTA score was evaluated by receiver operating characteristic analysis. Result: Ninety-four patients were enrolled in the final analysis. The patients with good collaterals had a smaller core volume (37.3 ± 24.7 vs. 116.5 ± 70 mL, p < 0.001) and lower HIR (0.51 ± 0.2 vs. 0.73 ± 0.13, p < 0.001) than those with poor collaterals. A higher HIR was correlated with a poorer collateral score by Pearson’s correlation. (r = −0.64, p < 0.001). The receiver operating characteristic (ROC) analysis suggested that the best HIR value for predicting a good collateral score was 0.68 (area under curve: 0.82). Conclusion: HIR is a good surrogate of collateral circulation in patients with acute large artery occlusion. View Full-Text
Keywords: hypoperfusion index ratio; collateral circulation; collateral scoring; CTA; CTP; large vessel occlusion hypoperfusion index ratio; collateral circulation; collateral scoring; CTA; CTP; large vessel occlusion
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MDPI and ACS Style

Wang, C.-M.; Chang, Y.-M.; Sung, P.-S.; Chen, C.-H. Hypoperfusion Index Ratio as a Surrogate of Collateral Scoring on CT Angiogram in Large Vessel Stroke. J. Clin. Med. 2021, 10, 1296. https://doi.org/10.3390/jcm10061296

AMA Style

Wang C-M, Chang Y-M, Sung P-S, Chen C-H. Hypoperfusion Index Ratio as a Surrogate of Collateral Scoring on CT Angiogram in Large Vessel Stroke. Journal of Clinical Medicine. 2021; 10(6):1296. https://doi.org/10.3390/jcm10061296

Chicago/Turabian Style

Wang, Chun-Min, Yu-Ming Chang, Pi-Shan Sung, and Chih-Hung Chen. 2021. "Hypoperfusion Index Ratio as a Surrogate of Collateral Scoring on CT Angiogram in Large Vessel Stroke" Journal of Clinical Medicine 10, no. 6: 1296. https://doi.org/10.3390/jcm10061296

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