Next Article in Journal
The Effect of Stress, Anxiety and Depression on In Vitro Fertilization Outcome in Kazakhstani Public Clinical Setting: A Cross-Sectional Study
Previous Article in Journal
Early Outcomes of Carotid Revascularization in Retrospective Case Series
 
 
Article

CPAP Therapy Termination Rates by OSA Phenotype: A French Nationwide Database Analysis

1
HP2 Laboratory, University Grenoble Alpes, Inserm, CHU Grenoble Alpes, 38043 Grenoble, France
2
SEMEIA, 75010 Paris, France
3
Faculty of Medicine, University of Geneva, 1205 Geneva, Switzerland
4
Pulmonary, Critical Care and Sleep Medicine, University of California, San Diego, CA 92037, USA
5
Charles Perkins Centre, Faculty of Medicine and Health, University Sydney, Sydney, NSW 2006, Australia
6
ResMed Science Center, Sydney, NSW 2153, Australia
7
ResMed Science Center, 69791 Saint Priest, France
*
Author to whom correspondence should be addressed.
Membership of the medXcloud Group is provided at www.medXcloud.org (accessed on 19 January 2021).
Academic Editors: Yuksel Peker and David J. Barnes
J. Clin. Med. 2021, 10(5), 936; https://doi.org/10.3390/jcm10050936
Received: 19 January 2021 / Revised: 20 February 2021 / Accepted: 22 February 2021 / Published: 1 March 2021
(This article belongs to the Section Pulmonology)
The nationwide claims data lake for sleep apnoea (ALASKA)—real-life data for understanding and increasing obstructive sleep apnea (OSA) quality of care study—investigated long-term continuous positive airway pressure (CPAP) termination rates, focusing on the contribution of comorbidities. The French national health insurance reimbursement system data for new CPAP users aged ≥18 years were analyzed. Innovative algorithms were used to determine the presence of specific comorbidities (hypertension, diabetes and chronic obstructive pulmonary disease (COPD)). Therapy termination was defined as cessation of CPAP reimbursements. A total of 480,000 patients were included (mean age 59.3 ± 13.6 years, 65.4% male). An amount of 50.7, 24.4 and 4.3% of patients, respectively, had hypertension, diabetes and COPD. Overall CPAP termination rates after 1, 2 and 3 years were 23.1, 37.1 and 47.7%, respectively. On multivariable analysis, age categories, female sex (1.09 (1.08–1.10) and COPD (1.12 (1.10–1.13)) and diabetes (1.18 (1.16–1.19)) were significantly associated with higher CPAP termination risk; patients with hypertension were more likely to continue using CPAP (hazard ratio 0.96 (95% confidence interval 0.95–0.97)). Therapy termination rates were highest in younger or older patients with ≥1 comorbidity. Comorbidities have an important influence on long-term CPAP continuation in patients with OSA. View Full-Text
Keywords: obstructive sleep apnea; continuous positive airway pressure; comorbidities; adherence; treatment obstructive sleep apnea; continuous positive airway pressure; comorbidities; adherence; treatment
Show Figures

Figure 1

MDPI and ACS Style

Pépin, J.-L.; Bailly, S.; Rinder, P.; Adler, D.; Szeftel, D.; Malhotra, A.; Cistulli, P.A.; Benjafield, A.; Lavergne, F.; Josseran, A.; Tamisier, R.; Hornus, P.; on behalf of the medXcloud Group. CPAP Therapy Termination Rates by OSA Phenotype: A French Nationwide Database Analysis. J. Clin. Med. 2021, 10, 936. https://doi.org/10.3390/jcm10050936

AMA Style

Pépin J-L, Bailly S, Rinder P, Adler D, Szeftel D, Malhotra A, Cistulli PA, Benjafield A, Lavergne F, Josseran A, Tamisier R, Hornus P, on behalf of the medXcloud Group. CPAP Therapy Termination Rates by OSA Phenotype: A French Nationwide Database Analysis. Journal of Clinical Medicine. 2021; 10(5):936. https://doi.org/10.3390/jcm10050936

Chicago/Turabian Style

Pépin, Jean-Louis, Sébastien Bailly, Pierre Rinder, Dan Adler, Daniel Szeftel, Atul Malhotra, Peter A. Cistulli, Adam Benjafield, Florent Lavergne, Anne Josseran, Renaud Tamisier, Pierre Hornus, and on behalf of the medXcloud Group. 2021. "CPAP Therapy Termination Rates by OSA Phenotype: A French Nationwide Database Analysis" Journal of Clinical Medicine 10, no. 5: 936. https://doi.org/10.3390/jcm10050936

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop