Positive Airway Pressure Therapy Adherence with Mask Resupply: A Propensity-Matched Analysis
Abstract
:1. Introduction
2. Methods
2.1. Study Design and Participants
2.2. Endpoints
2.3. Statistical Analysis
3. Results
3.1. Study Sample
3.2. Resupply
3.3. Adherence
3.4. Respiratory Parameters
3.5. Sensitivity Analysis
3.6. Longitudinal Analysis
4. Discussion
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Heading | Control (n = 50,185) | Resupply (n = 50,185) |
---|---|---|
Age, years | ||
Mean ± SD | 56.9 ± 13.6 | 57.0 ± 13.5 |
Median | 57.0 | 57.0 |
Sex, n (%) | ||
Female | 17,847 (35.6) | 17,858 (35.6) |
Male | 32,312 (64.4) | 32,301 (64.4) |
Missing | 26 (<0.1) | 26 (<0.1) |
Device/mode, n (%) | ||
APAP | 21,437 (42.7) | 21,449 (42.7) |
CPAP | 23,949 (47.7) | 24,022 (47.9) |
Bilevel | 4272 (8.5) | 4187 (8.3) |
Missing | 527 (1.1) | 527 (1.1) |
myAirTM use, n (%) | 8807 (17.5) | 8795 (17.5) |
AHI on the first day of therapy, /h | ||
Mean ± SD | 3.9 ± 6.0 | 3.8 ± 5.7 |
Median | 2.0 | 2.0 |
95th percentile leak on the first day of therapy, L/min | ||
Mean ± SD | 23.5 ± 26.3 | 23.2 ± 25.7 |
Median | 15.6 | 15.6 |
Device Usage | Control | Resupply | p-Value |
---|---|---|---|
(n = 50,185) | (n = 50,185) | ||
Mean usage, h | |||
Mean (SE) | 4.5 (0.1) | 5.6 (0.01) | |
Median | 4.9 | 6.0 | |
Mean difference vs. control (95% CI) | 1.1 (1.06, 1.13) | <0.0001 | |
Mean usage ≥4 h, % | |||
Mean (95% CI) | 59.2 (58.8, 59.6) | 77.0 (76.6, 77.4) | |
Mean difference vs. control (95% CI) | 17.8 (17.2, 18.3) | <0.0001 | |
Daily usage ≥4 h for 70% of nights, % | |||
Mean (95% CI) | 50.9 (50.5, 51.3) | 67.7 (67.3, 68.1) | |
Mean difference vs. control (95% CI) | 16.8 (16.2, 17.4) | <0.0001 | |
Respiratory Parameters | (n = 47,373) | (n = 49,359) | |
Mean AHI, /h | |||
Mean (SE) | 2.6 (0.02) | 2.5 (0.01) | |
Median | 1.5 | 1.5 | |
Mean difference vs. control (95% CI) | −0.2 (−0.21, −0.13) | <0.0001 | |
Median 95% percentile mask leak, L/min | |||
Mean (SE) | 20.4 (0.10) | 19.0 (0.09) | |
Median | 15.0 | 14.4 | |
Mean difference vs. control (95% CI) | −1.5 (−1.68, −1.24) | <0.0001 |
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Benjafield, A.V.; Oldstone, L.M.; Willes, L.A.; Kelly, C.; Nunez, C.M.; Malhotra, A.; on behalf of the medXcloud Group. Positive Airway Pressure Therapy Adherence with Mask Resupply: A Propensity-Matched Analysis. J. Clin. Med. 2021, 10, 720. https://doi.org/10.3390/jcm10040720
Benjafield AV, Oldstone LM, Willes LA, Kelly C, Nunez CM, Malhotra A, on behalf of the medXcloud Group. Positive Airway Pressure Therapy Adherence with Mask Resupply: A Propensity-Matched Analysis. Journal of Clinical Medicine. 2021; 10(4):720. https://doi.org/10.3390/jcm10040720
Chicago/Turabian StyleBenjafield, Adam V., Liesl M. Oldstone, Leslee A. Willes, Colleen Kelly, Carlos M. Nunez, Atul Malhotra, and on behalf of the medXcloud Group. 2021. "Positive Airway Pressure Therapy Adherence with Mask Resupply: A Propensity-Matched Analysis" Journal of Clinical Medicine 10, no. 4: 720. https://doi.org/10.3390/jcm10040720