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Clinical Features and Diagnosis of Cardiac Sarcoidosis

Novelties in Imaging of Thoracic Sarcoidosis

Department of Diagnostic Imaging, Oncological Radiotherapy and Hematology, Fondazione Policlinico Universitario “A. Gemelli” IRCCS, 00168 Rome, Italy
Section of Radiology, Department of Radiological and Hematological Sciences, Università Cattolica del Sacro Cuore, 00168 Rome, Italy
Pulmonary Medicine Unit, Department of Medical and Surgical Sciences, Fondazione Policlinico Universitario “A. Gemelli” IRCCS, 00168 Rome, Italy
Author to whom correspondence should be addressed.
Academic Editors: Philippe Guilpain and Cosima Schiavone
J. Clin. Med. 2021, 10(11), 2222;
Received: 15 April 2021 / Revised: 14 May 2021 / Accepted: 19 May 2021 / Published: 21 May 2021
(This article belongs to the Special Issue New Frontiers in the Diagnosis of Sarcoidosis)
Sarcoidosis is a systemic granulomatous disease affecting various organs, and the lungs are the most commonly involved. According to guidelines, diagnosis relies on a consistent clinical picture, histological demonstration of non-caseating granulomas, and exclusion of other diseases with similar histological or clinical picture. Nevertheless, chest imaging plays an important role in both diagnostic assessment, allowing to avoid biopsy in some situations, and prognostic evaluation. Despite the demonstrated lower sensitivity of chest X-ray (CXR) in the evaluation of chest findings compared to high-resolution computed tomography (HRCT), CXR still retains a pivotal role in both diagnostic and prognostic assessment in sarcoidosis. Moreover, despite the huge progress made in the field of radiation dose reduction, chest magnetic resonance (MR), and quantitative imaging, very little research has focused on their application in sarcoidosis. In this review, we aim to describe the latest novelties in diagnostic and prognostic assessment of thoracic sarcoidosis and to identify the fields of research that require investigation. View Full-Text
Keywords: sarcoidosis; HRCT; prognostic assessment; CXR; radiomics; chest MR sarcoidosis; HRCT; prognostic assessment; CXR; radiomics; chest MR
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MDPI and ACS Style

Calandriello, L.; D’Abronzo, R.; Pasciuto, G.; Cicchetti, G.; del Ciello, A.; Farchione, A.; Strappa, C.; Manfredi, R.; Larici, A.R. Novelties in Imaging of Thoracic Sarcoidosis. J. Clin. Med. 2021, 10, 2222.

AMA Style

Calandriello L, D’Abronzo R, Pasciuto G, Cicchetti G, del Ciello A, Farchione A, Strappa C, Manfredi R, Larici AR. Novelties in Imaging of Thoracic Sarcoidosis. Journal of Clinical Medicine. 2021; 10(11):2222.

Chicago/Turabian Style

Calandriello, Lucio, Rosa D’Abronzo, Giuliana Pasciuto, Giuseppe Cicchetti, Annemilia del Ciello, Alessandra Farchione, Cecilia Strappa, Riccardo Manfredi, and Anna Rita Larici. 2021. "Novelties in Imaging of Thoracic Sarcoidosis" Journal of Clinical Medicine 10, no. 11: 2222.

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