Progress and Prospects on Vaccine Development against SARS-CoV-2
Abstract
:1. Introduction
2. Antigen Selection
2.1. Whole Cell Antigens
2.2. Spike Protein (S Protein)
2.2.1. The Full-Length S Protein
2.2.2. RBD
2.2.3. NTD
2.2.4. S1 Subunit
2.2.5. FP
2.3. Nucleocapsid Protein (N Protein)
2.4. Membrane Protein (M Protein)
2.5. Envelope Protein (E Protein)
3. Different Types of SARS-CoV-2 Vaccines under Development
3.1. Whole-Cell Killed and Live-Attenuated Vaccines
3.2. Subunit Vaccines
3.3. mRNA Vaccines
3.4. DNA Vaccine
3.5. Live Vector Vaccines
3.6. Synthetic Peptide or Epitope Vaccine
4. Means of Efficacy Evaluation
5. Adjuvant
6. Safety Concerns
7. Prospects
Funding
Conflicts of Interest
References
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Zhang, J.; Zeng, H.; Gu, J.; Li, H.; Zheng, L.; Zou, Q. Progress and Prospects on Vaccine Development against SARS-CoV-2. Vaccines 2020, 8, 153. https://doi.org/10.3390/vaccines8020153
Zhang J, Zeng H, Gu J, Li H, Zheng L, Zou Q. Progress and Prospects on Vaccine Development against SARS-CoV-2. Vaccines. 2020; 8(2):153. https://doi.org/10.3390/vaccines8020153
Chicago/Turabian StyleZhang, Jinyong, Hao Zeng, Jiang Gu, Haibo Li, Lixin Zheng, and Quanming Zou. 2020. "Progress and Prospects on Vaccine Development against SARS-CoV-2" Vaccines 8, no. 2: 153. https://doi.org/10.3390/vaccines8020153