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Andrographolide, a Natural Antioxidant: An Update

Laboratory I3MTO, EA 4708, Université d’Orléans, 45067 Orléans Cedex 2, France
Service de Rhumatologie, Centre Hospitalier Régional d’Orléans 14 Avenue de l’Hôpital, 45100 Orléans, France
Plateforme Recherche Innovation Médicale Mutualisée d’Orléans, Centre Hospitalier Régional d’Orléans CHRO, 41220 St Laurent Nouan, France
NOVAXIA-6 Rue des champs Godin, 41220 St Laurent Nouan, France
Institut de Chimie Organique et Analytique, Université d’Orléans-Pôle de Chimie, UMR CNRS 7311, Rue de Chartres, 45067 Orléans, France
Author to whom correspondence should be addressed.
Antioxidants 2019, 8(12), 571;
Received: 22 October 2019 / Revised: 13 November 2019 / Accepted: 15 November 2019 / Published: 20 November 2019
Traditionally, Andrographis paniculata has been used as an herbal remedy for lung infection treatments. Its leaves contain a diterpenoid labdane called andrographolide responsible for a wide range of biological activities such as antioxidant, anti-inflammatory, and anti-cancer properties. This manuscript is a brief review of the antioxidant mechanisms and the regulation of the Nrf2 (nuclear factor (erythroid-derived 2)-like 2) signaling pathway by andrographolide.
Keywords: Andrographis paniculata; andrographolide; oxidative stress; Nrf2 Andrographis paniculata; andrographolide; oxidative stress; Nrf2
MDPI and ACS Style

Mussard, E.; Cesaro, A.; Lespessailles, E.; Legrain, B.; Berteina-Raboin, S.; Toumi, H. Andrographolide, a Natural Antioxidant: An Update. Antioxidants 2019, 8, 571.

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