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Andrographolide, a Natural Antioxidant: An Update

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Laboratory I3MTO, EA 4708, Université d’Orléans, 45067 Orléans Cedex 2, France
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Service de Rhumatologie, Centre Hospitalier Régional d’Orléans 14 Avenue de l’Hôpital, 45100 Orléans, France
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Plateforme Recherche Innovation Médicale Mutualisée d’Orléans, Centre Hospitalier Régional d’Orléans CHRO, 41220 St Laurent Nouan, France
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NOVAXIA-6 Rue des champs Godin, 41220 St Laurent Nouan, France
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Institut de Chimie Organique et Analytique, Université d’Orléans-Pôle de Chimie, UMR CNRS 7311, Rue de Chartres, 45067 Orléans, France
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Author to whom correspondence should be addressed.
Antioxidants 2019, 8(12), 571; https://doi.org/10.3390/antiox8120571
Received: 22 October 2019 / Revised: 13 November 2019 / Accepted: 15 November 2019 / Published: 20 November 2019
Traditionally, Andrographis paniculata has been used as an herbal remedy for lung infection treatments. Its leaves contain a diterpenoid labdane called andrographolide responsible for a wide range of biological activities such as antioxidant, anti-inflammatory, and anti-cancer properties. This manuscript is a brief review of the antioxidant mechanisms and the regulation of the Nrf2 (nuclear factor (erythroid-derived 2)-like 2) signaling pathway by andrographolide.
Keywords: Andrographis paniculata; andrographolide; oxidative stress; Nrf2 Andrographis paniculata; andrographolide; oxidative stress; Nrf2
MDPI and ACS Style

Mussard, E.; Cesaro, A.; Lespessailles, E.; Legrain, B.; Berteina-Raboin, S.; Toumi, H. Andrographolide, a Natural Antioxidant: An Update. Antioxidants 2019, 8, 571.

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