Next Article in Journal
Tissue Plasminogen Activator and MRI Signs of Cerebral Small Vessel Disease
Previous Article in Journal
Weight Change after Striatal/Capsule Deep Brain Stimulation Relates to Connectivity to the Bed Nucleus of the Stria Terminalis and Hypothalamus
Previous Article in Special Issue
Rapid Communication: Plasma Interleukin-35 in Children with Autism
Open AccessReview

Autism Spectrum Disorder and miRNA: An Overview of Experimental Models

IRCCS Centro Neurolesi “Bonino-Pulejo”, Via Provinciale Palermo, Contrada Casazza, 98124 Messina, Italy
*
Author to whom correspondence should be addressed.
Brain Sci. 2019, 9(10), 265; https://doi.org/10.3390/brainsci9100265
Received: 20 August 2019 / Revised: 25 September 2019 / Accepted: 2 October 2019 / Published: 3 October 2019
Autism spectrum disorder (ASD) is a complex neuropsychiatric disorder characterized by deficits in social interactions, communication, language, and in a limited repertoire of activities and interests. The etiology of ASD is very complex. Genetic, epigenetic, and environmental factors contribute to the onset of ASD. Researchers have shown that microRNAs (miRNAs) could be one of the possible causes associated with ASD. miRNAs are small noncoding mRNAs that regulate gene expression, and they are often linked to biological processes and implicated in neurodevelopment. This review aims to provide an overview of the animal models and the role of the different miRNAs involved in ASD. Therefore, the use of animal models that reproduce the ASD and the identification of miRNAs could be a useful predictive tool to study this disorder. View Full-Text
Keywords: autism spectrum disorder; miRNA; experimental models autism spectrum disorder; miRNA; experimental models
MDPI and ACS Style

Schepici, G.; Cavalli, E.; Bramanti, P.; Mazzon, E. Autism Spectrum Disorder and miRNA: An Overview of Experimental Models. Brain Sci. 2019, 9, 265.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop