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Brain Sciences
  • Correction
  • Open Access

14 November 2025

Correction: López-Manzanares et al. Real-World Use of COMT Inhibitors in the Management of Patients with Parkinson’s Disease in Spain Who Present Early Motor Fluctuations: Interim Results from the REONPARK Study. Brain Sci. 2025, 15, 532

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1
Movement Disorders Unit, Department of Neurology, University Hospital La Princesa, 28006 Madrid, Spain
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Neurology Service, Hospital Quirónsalud Palmaplanas and Clínica Rotger, 07010 Palma de Mallorca, Spain
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Department of Neurology, University Hospital Infanta Sofia, 28702 Madrid, Spain
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Department of Neurology, University Hospital Germans Trias i Pujol, 08916 Barcelona, Spain
Brain Sci.2025, 15(11), 1225;https://doi.org/10.3390/brainsci15111225 
(registering DOI)

Text Correction

There was an error in the original publication []. In the Introduction Section, the following referenced sentence contains a misinterpretation: “Moreover, recent findings have indicated the benefit of adding opicapone at 50 mg to an additional 100 mg of levodopa in reducing OFF times in a cohort with early fluctuations [19]”. The sentence incorrectly suggests that the benefit arises from combining opicapone 50 mg with an additional 100 mg of levodopa, thus attributing to the referenced work a statement that differs from their original text. The correct interpretation is that opicapone 50 mg was more effective than an additional 100 mg of levodopa in reducing OFF time.
A correction has been made to the 5th paragraph of the Introduction Section.
The revised paragraph reads as follows: “Moreover, recent findings have indicated that adding opicapone 50 mg is more beneficial than adding an additional 100 mg of levodopa in reducing OFF times in a cohort with early fluctuations [19].”
The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated.

Reference

  1. López-Manzanares, L.; García Caldentey, J.; Álvarez-Santullano, M.M.; Vilas Rolán, D.; Herreros-Rodríguez, J.; Solano Vila, B.; Cerdán Sánchez, M.; Delgado Ballestero, T.; García-Ramos, R.; Rodríguez-Sanz, A.; et al. Real-World Use of COMT Inhibitors in the Management of Patients with Parkinson’s Disease in Spain Who Present Early Motor Fluctuations: Interim Results from the REONPARK Study. Brain Sci. 2025, 15, 532. [Google Scholar] [CrossRef] [PubMed]
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