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Development of a Stationary 3D Photoacoustic Imaging System Using Sparse Single-Element Transducers: Phantom Study

Department of Biomedical Engineering, Wayne State University, Detroit, MI 48201, USA
Department of Physics, University of Isfahan, Isfahan 81746-73441, Iran
Department of Imaging Physics, Laboratory of Acoustical Wavefield Imaging, Delft University of Technology, 2628 CD Delft, The Netherlands
Department of Biomedical Engineering, Thorax Center, Erasmus Medical Center, 3015 Rotterdam, The Netherlands
Department of Biomedical Engineering, Nanjing Medical University, Nanjing 210029, China
Department of Neurology, Wayne State University School of Medicine, Detroit, MI 48201, USA
Barbara Ann Karmanos Cancer Institute, Detroit, MI 48201, USA
Author to whom correspondence should be addressed.
Appl. Sci. 2019, 9(21), 4505;
Received: 8 June 2019 / Revised: 11 October 2019 / Accepted: 19 October 2019 / Published: 24 October 2019
(This article belongs to the Special Issue Biomedical Photoacoustic and Thermoacoustic Imaging)
Photoacoustic imaging (PAI) is an emerging label-free and non-invasive modality for imaging biological tissues. PAI has been implemented in different configurations, one of which is photoacoustic computed tomography (PACT) with a potential wide range of applications, including brain and breast imaging. Hemispherical Array PACT (HA-PACT) is a variation of PACT that has solved the limited detection-view problem. Here, we designed an HA-PACT system consisting of 50 single element transducers. For implementation, we initially performed a simulation study, with parameters close to those in practice, to determine the relationship between the number of transducers and the quality of the reconstructed image. We then used the greatest number of transducers possible on the hemisphere and imaged copper wire phantoms coated with a light absorbing material to evaluate the performance of the system. Several practical issues such as light illumination, arrangement of the transducers, and an image reconstruction algorithm have been comprehensively studied. View Full-Text
Keywords: PACT; hemisphere; low-cost; homogenous PACT; hemisphere; low-cost; homogenous
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Kratkiewicz, K.; Manwar, R.; Zafar, M.; Mohsen Ranjbaran, S.; Mozaffarzadeh, M.; de Jong, N.; Ji, K.; Avanaki, K. Development of a Stationary 3D Photoacoustic Imaging System Using Sparse Single-Element Transducers: Phantom Study. Appl. Sci. 2019, 9, 4505.

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