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Appl. Sci. 2017, 7(1), 60;

Biodegradable and Biocompatible Systems Based on Hydroxyapatite Nanoparticles

B. Braun Surgical S.A., Carretera de Terrassa 121, Rubí 08191, Spain
Chemical Engineering Department, Escola d’Enginyeria de Barcelona Est-EEBE, c/Eduard Maristany 10-14, Barcelona 08019, Spain
Authors to whom correspondence should be addressed.
Academic Editor: Patrick A. Fairclough
Received: 7 November 2016 / Revised: 19 December 2016 / Accepted: 23 December 2016 / Published: 6 January 2017
(This article belongs to the Special Issue Biodegradable and Biocompatible Nanoparticles)
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Composites of hydroxyapatite (HAp) are widely employed in biomedical applications due to their biocompatibility, bioactivity and osteoconductivity properties. In fact, the development of industrially scalable hybrids at low cost and high efficiency has a great impact, for example, on bone tissue engineering applications and even as drug delivery systems. New nanocomposites constituted by HAp nanoparticles and synthetic or natural polymers with biodegradable and biocompatible characteristics have constantly been developed and extensive works have been published concerning their applications. The present review is mainly focused on both the capability of HAp nanoparticles to encapsulate diverse compounds as well as the preparation methods of scaffolds incorporating HAp. Attention has also been paid to the recent developments on antimicrobial scaffolds, bioactive membranes, magnetic scaffolds, in vivo imaging systems, hydrogels and coatings that made use of HAp nanoparticles. View Full-Text
Keywords: nanoparticles; hydroxyapatite; drug delivery; scaffolds; non-viral vectors nanoparticles; hydroxyapatite; drug delivery; scaffolds; non-viral vectors

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Turon, P.; del Valle, L.J.; Alemán, C.; Puiggalí, J. Biodegradable and Biocompatible Systems Based on Hydroxyapatite Nanoparticles. Appl. Sci. 2017, 7, 60.

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