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Appl. Sci. 2016, 6(11), 319;

Extraction of Glycyrrhizic Acid from Glycyrrhiza uralensis Using Ultrasound and Its Process Extraction Model

Key Laboratory of Industrial Advanced Process Control for Light Industry of Ministry of Education, Jiangnan University, Wuxi 214122, China
Department of Physics and Electrical Engineering, Ningde Normal University, Ningde 352100, China
School of Chemical and Environment Science, Shaanxi University of Technology, Hanzhong 723001, China
Author to whom correspondence should be addressed.
Academic Editor: Chih-Ching Huang
Received: 19 September 2016 / Revised: 19 October 2016 / Accepted: 21 October 2016 / Published: 26 October 2016
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This work focused on the intensification of extraction process of glycyrrhizic acid (GA) from Glycyrrhiza uralensis using ultrasound-assisted extraction (UAE) method. Various process parameters such as ultrasonic power, ultrasonic frequency, extraction temperature, and extraction time which affect the extraction yield were optimized. The results showed that all process parameters had exhibited significant influences on the GA extraction. The highest GA yield of 217.7 mg/g was obtained at optimized parameters of 125 W, 55 kHz, 25 °C, and 10 min. Furthermore, the extraction kinetics model of this process was also investigated based on Fick’s first law available in the literature. Kinetic parameters such as equilibrium concentration (Ce) and integrated influence coefficient (λ) for different ultrasonic powers, ultrasonic frequencies, and extraction temperatures were predicted. Model validations were done successfully with the average of relative deviation between 0.96% and 4.36% by plotting experimental and predicted values of concentration of GA in extract. This indicated that the developed extraction model could reflect the effectiveness of the extraction of GA from Glycyrrhiza uralensis and therefore serve as the guide for comprehending other UAE process. View Full-Text
Keywords: ultrasound; extraction; glycyrrhizic acid; Glycyrrhiza uralensis; model ultrasound; extraction; glycyrrhizic acid; Glycyrrhiza uralensis; model

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Liao, J.; Qu, B.; Zheng, N. Extraction of Glycyrrhizic Acid from Glycyrrhiza uralensis Using Ultrasound and Its Process Extraction Model. Appl. Sci. 2016, 6, 319.

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