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Open AccessCommunication

Microwave-Assisted Synthesis and Antifungal Activity of Some Novel Thioethers Containing 1,2,4-Triazole Moiety

1
College of Life Science, Huzhou University, Huzhou 313000, China
2
Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing 100014, China
3
College of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310014, China
4
Ecology Institute of Shandong Academy of Science, Jinan 250014, China
*
Authors to whom correspondence should be addressed.
These authors contributed equally to this work.
Academic Editor: Rajender S. Varma
Appl. Sci. 2015, 5(4), 1211-1220; https://doi.org/10.3390/app5041211
Received: 8 October 2015 / Revised: 3 November 2015 / Accepted: 11 November 2015 / Published: 16 November 2015
A series of novel thioether derivatives containing 1,2,4-triazole moiety were designed and synthesized from 4-chlorophenol and ethyl 2-chloroacetate as starting materials by multi-step reactions under microwave irradiation, and their structures were characterized by 1H-NMR, MS and elemental analysis. The antifungal activity of title compounds was determined. The results indicated that some of title compounds exhibited moderate antifungal activity. View Full-Text
Keywords: thioether; 1,2,4-triazole; microwave assistant synthesis; antifungal activity thioether; 1,2,4-triazole; microwave assistant synthesis; antifungal activity
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MDPI and ACS Style

Min, L.-J.; Shi, Y.-X.; Wu, H.-K.; Sun, Z.-H.; Liu, X.-H.; Li, B.-J.; Zhang, Y.-G. Microwave-Assisted Synthesis and Antifungal Activity of Some Novel Thioethers Containing 1,2,4-Triazole Moiety. Appl. Sci. 2015, 5, 1211-1220.

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