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Article

Blurred Lesion Image Segmentation via an Adaptive Scale Thresholding Network

by
Qi Chen
,
Wenmin Wang
*,
Zhibing Wang
,
Haomei Jia
and
Minglu Zhao
School of Computer Science and Engineering, Macau University of Science and Technology, Macau, China
*
Author to whom correspondence should be addressed.
Appl. Sci. 2025, 15(17), 9259; https://doi.org/10.3390/app15179259
Submission received: 28 July 2025 / Revised: 19 August 2025 / Accepted: 21 August 2025 / Published: 22 August 2025

Abstract

Medical image segmentation is crucial for disease diagnosis, as precise results aid clinicians in locating lesion regions. However, lesions often have blurred boundaries and complex shapes, challenging traditional methods in capturing clear edges and impacting accurate localization and complete excision. Small lesions are also critical but prone to detail loss during downsampling, reducing segmentation accuracy. To address these issues, we propose a novel adaptive scale thresholding network (AdSTNet) that acts as a post-processing lightweight network for enhancing sensitivity to lesion edges and cores through a dual-threshold adaptive mechanism. The dual-threshold adaptive mechanism is a key architectural component that includes a main threshold map for core localization and an edge threshold map for more precise boundary detection. AdSTNet is compatible with any segmentation network and introduces only a small computational and parameter cost. Additionally, Spatial Attention and Channel Attention (SACA), the Laplacian operator, and the Fusion Enhancement module are introduced to improve feature processing. SACA enhances spatial and channel attention for core localization; the Laplacian operator retains edge details without added complexity; and the Fusion Enhancement module adapts concatenation operation and Convolutional Gated Linear Unit (ConvGLU) to improve feature intensities to improve edge and small lesion segmentation. Experiments show that AdSTNet achieves notable performance gains on ISIC 2018, BUSI, and Kvasir-SEG datasets. Compared with the original U-Net, our method attains mIoU/mDice of 83.40%/90.24% on ISIC, 71.66%/80.32% on BUSI, and 73.08%/81.91% on Kvasir-SEG. Moreover, similar improvements are observed in the rest of the networks.
Keywords: blurred lesion image segmentation; small lesion segmentation; adaptive scale threshold maps; medical image segmentation blurred lesion image segmentation; small lesion segmentation; adaptive scale threshold maps; medical image segmentation

Share and Cite

MDPI and ACS Style

Chen, Q.; Wang, W.; Wang, Z.; Jia, H.; Zhao, M. Blurred Lesion Image Segmentation via an Adaptive Scale Thresholding Network. Appl. Sci. 2025, 15, 9259. https://doi.org/10.3390/app15179259

AMA Style

Chen Q, Wang W, Wang Z, Jia H, Zhao M. Blurred Lesion Image Segmentation via an Adaptive Scale Thresholding Network. Applied Sciences. 2025; 15(17):9259. https://doi.org/10.3390/app15179259

Chicago/Turabian Style

Chen, Qi, Wenmin Wang, Zhibing Wang, Haomei Jia, and Minglu Zhao. 2025. "Blurred Lesion Image Segmentation via an Adaptive Scale Thresholding Network" Applied Sciences 15, no. 17: 9259. https://doi.org/10.3390/app15179259

APA Style

Chen, Q., Wang, W., Wang, Z., Jia, H., & Zhao, M. (2025). Blurred Lesion Image Segmentation via an Adaptive Scale Thresholding Network. Applied Sciences, 15(17), 9259. https://doi.org/10.3390/app15179259

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