Evaluation of the Failure Rate and Clinical Efficacy of Orthodontic Brackets Indirect Bonding with Computer-Aided Transfer Jig System: An In Vivo Study
Round 1
Reviewer 1 Report
This manuscript designed and conducted a clinical study to evaluate the failure rates and relevant factors of the bonded orthodontic brackets with computer-aided design and manufacturing based 3D-printed indirect bonding jig system. The authors applied the multiple linear regression analysis to evaluate the association between bracket bonding failure rate and patients’ age, sex, treatment stage, skeletal divergence, and tooth position. The results show that the patients’ gender, age and treatment stages were highly related with all the re-bonding rate. It is also found that anterior teeth shown higher position error rate than premolars and molars. Patients with the hyper-divergent skeletal pattern had higher brackets bonding failure rate. The results of this study can potentially provide clinical and practical guidelines in placing brackets with 3d-printed IDBS with high precision and accuracy in future treatment. Overall this manuscript is well organized and written, and the acceptance of this manuscript is accepted.
Author Response
Thank you deeply for your considerate comments.
Reviewer 2 Report
Dear Authors,
I have read and reviewed the manuscript with interest, it is a well-written manuscript, and the data are nicely presented. I have only one comment regarding the material used for cementing or luting the bracket. It's not clearly presented in the text and not adequately discussed. The effect of different luting materials like GIC or resin cement might have an impact on the debonding rate.
Please review the writing style of the Journal
Thank you
Author Response
Thank you for your valuable comments. we presented the type of orthodontic adhesive used in this study and analyzed its influence for this study in the section of discussion. We supplement and explicitly describe the properties of the adhesive used in this study and discussed its influences in this study.
“After the light curing resin adhesive (Transbond™ XT Light Cure Adhesive, 3M Unitek, Monrovia, CA, USA) was applied on the bracket base, putted the IDB jig with the bracket was bonded on the tooth by light curing device (VALO, Ultradent, South Jor-dan, UT, USA). “
Reviewer 3 Report
The manuscript needs minor revision.
Introduction: Introduction section is short. Pleases improve it and compare the IDBS with direct bonding technique.
Materials & Methods: Pleases mention sample size calculation and sampling strategy
Discussion: In the discussion section I would like to see a more profound discussion about the findings. What is the meaning of your results in light of earlier studies?
References: You could increase the number of more recently studies in the introduction and discussion sections
Author Response
The manuscript needs minor revision.
- Introduction: Introduction section is short. Pleases improve it and compare the IDBS with direct bonding technique.
In this part, we supplement the description of the characteristics of IDBS by comparing direct bonding technique.
- Materials & Methods: Pleases mention sample size calculation and sampling strategy
We supplement the description of the sample size and sampling strategy.
- Discussion: In the discussion section I would like to see a more profound discussion about the findings. What is the meaning of your results in light of earlier studies?
We had conducted a more profound discussion on the results of our study in the light of previous researches.
- References: You could increase the number of more recently studies in the introduction and discussion sections
In this section, we added the references which cited in the Supplementary Section of the manuscript after revisions. And for the supplement part, we cited more recently researches as possible
Reviewer 4 Report
The article is interesting and innovative. However, there is an important limitation in the study, which is only specified at the end of the discussion and which cannot be overlooked because it is not incidental, and that is that the cementing of the brackets was not performed by the same operator, which can condition the results of the investigation. It would be appropriate to specify, in material and method, this limitation by indicating the degree of professional experience of the operators (in years, training, etc). Likewise, the reference to this limitation should be briefly developed in the discussion with some comparison to the scientific literature.
Author Response
Thank you for your valuable comments.
We supplement the identity, professional ability and training level of the operators.
We further discussed the influence of the technical sensitivity from different operators in this study. And proposed the improvement direction for the follow-up research.
“All the operators were the national board-certified orthodontists and trained from the Kyung Hee University Dental Hospital Biocreative Orthodontic Center.”
