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Applied Sciences
Volume 11
Issue 19
10.3390/app11199019
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Review

Metal Nanozymes: New Horizons in Cellular Homeostasis Regulation

by
Hanna Lewandowska
1,*,
Karolina Wójciuk
2 and
Urszula Karczmarczyk
3,*
1
Institute of Nuclear Chemistry and Technology, 16 Dorodna St., 03-195 Warsaw, Poland
2
National Centre for Nuclear Research, Andrzeja Soltana 7, 05-400 Otwock, Poland
3
Radioisotope Centre POLATOM, National Centre for Nuclear Research, Andrzeja Sołtana 7, 05-400 Otwock, Poland
*
Authors to whom correspondence should be addressed.
Appl. Sci. 2021, 11(19), 9019; https://doi.org/10.3390/app11199019
Submission received: 6 September 2021 / Revised: 23 September 2021 / Accepted: 24 September 2021 / Published: 28 September 2021
(This article belongs to the Special Issue Metals and Metal Complexes in Cell Signaling)
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Abstract

Nanomaterials with enzyme-like activity (nanozymes) have found applications in various fields of medicine, industry, and environmental protection. This review discusses the use of nanozymes in the regulation of cellular homeostasis. We also review the latest biomedical applications of nanozymes related to their use in cellular redox status modification and detection. We present how nanozymes enable biomedical advances and demonstrate basic design strategies to improve diagnostic and therapeutic efficacy in various diseases. Finally, we discuss the current challenges and future directions for developing nanozymes for applications in the regulation of the redox-dependent cellular processes and detection in the cellular redox state changes.
Keywords: metals; metal oxides; metal nanozymes; homeostasis; oxidative stress metals; metal oxides; metal nanozymes; homeostasis; oxidative stress

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MDPI and ACS Style

Lewandowska, H.; Wójciuk, K.; Karczmarczyk, U. Metal Nanozymes: New Horizons in Cellular Homeostasis Regulation. Appl. Sci. 2021, 11, 9019. https://doi.org/10.3390/app11199019

AMA Style

Lewandowska H, Wójciuk K, Karczmarczyk U. Metal Nanozymes: New Horizons in Cellular Homeostasis Regulation. Applied Sciences. 2021; 11(19):9019. https://doi.org/10.3390/app11199019

Chicago/Turabian Style

Lewandowska, Hanna, Karolina Wójciuk, and Urszula Karczmarczyk. 2021. "Metal Nanozymes: New Horizons in Cellular Homeostasis Regulation" Applied Sciences 11, no. 19: 9019. https://doi.org/10.3390/app11199019

APA Style

Lewandowska, H., Wójciuk, K., & Karczmarczyk, U. (2021). Metal Nanozymes: New Horizons in Cellular Homeostasis Regulation. Applied Sciences, 11(19), 9019. https://doi.org/10.3390/app11199019

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