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Open AccessArticle

Variance of the Gait Parameters and Fraction of Double-Support Interval for Determining the Severity of Parkinson’s Disease

1
Biosignals Lab., School of Engineering, RMIT University, GPO Box 2476, Melbourne, VIC 3001, Australia
2
Center for Human Movement Research and Analysis, Department of Electronics and Instrumentation Engineering, SRM Institute of Science and Technology, Chennai 603203, India
*
Author to whom correspondence should be addressed.
Appl. Sci. 2020, 10(2), 577; https://doi.org/10.3390/app10020577
Received: 12 December 2019 / Revised: 7 January 2020 / Accepted: 10 January 2020 / Published: 13 January 2020
The aim of this study was to determine the gait features that are most suitable for the quantified assessment of the severity of Parkinson’s disease (PD). This study computed the mean and variance of the four phases of gait intervals, i.e., stride, swing, stance and double-support intervals, and lateral difference to determine the difference between three groups, i.e., control subjects and PD patients with two severity levels (early and advanced stage) of the disease, PD1 and PD2. Data from 31 subjects were used in the study. The data were obtained from the public database (16 control healthy subjects, 6 Parkinson’s disease patients with early stages, and 9 Parkinson’s disease patients with advanced stages based on the Hoehn and Yahr scale). The main outcome measure of the study was the group difference of the four gait interval parameters and the statistical significance of this difference. The results show that there was a significant increase in the variance of the four gait intervals with the severity of the disease. However, there was no significant difference in the mean values between the three groups. It was also observed that the fraction corresponding to the double-support interval was significantly higher for PD patients. This study has shown that the variance of the gait parameters and the fraction of double-support interval are associated with the severity of PD and may be suitable measures for a quantified evaluation of the disease. View Full-Text
Keywords: gait; double support; Parkinson’s disease; variance; lateral differences gait; double support; Parkinson’s disease; variance; lateral differences
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Keloth, S.M.; Arjunan, S.P.; Kumar, D.K. Variance of the Gait Parameters and Fraction of Double-Support Interval for Determining the Severity of Parkinson’s Disease. Appl. Sci. 2020, 10, 577.

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