Barriers and Facilitators to the Implementation of Evidence-Based Lifestyle Management in Polycystic Ovary Syndrome: A Narrative Review
Round 1
Reviewer 1 Report
Overall this is a comprehensive narrative review detailing the challenges of implementing a lifestyle program in PCOS. As the authors note the recommendations are heavily based on practice in Australia and as such may not be uniformly applicable to other healthcare systems. This should be better emphasized in the discussion. Additional points:
How were the studies selected for inclusion in Table 1--how many were reviewed and excluded as this is not comprehensive?
Regarding the role of healthcare professionals, you should note the following reference:
A W Lin, E J Bergomi, J S Dollahite, J Sobal, K M Hoeger, M E Lujan, Trust in Physicians and Medical Experience Beliefs Differ Between Women With and Without Polycystic Ovary Syndrome, Journal of the Endocrine Society, Volume 2, Issue 9, September 2018, Pages 1001–1009, https://doi.org/10.1210/js.2018-00181
This concludes women with PCOS reported greater overall distrust in the PCP’s opinions and more arguments with their health care providers than women without PCOS, which may influence some of your recommendations.
Author Response
Dear reviewer 1 and editor,
Thank you for the constructive feedback. Please see below our response to your comments and suggestions:
Comments and suggestions | Responses |
Reviewer 1 | |
Overall this is a comprehensive narrative review detailing the challenges of implementing a lifestyle program in PCOS. As the authors note the recommendations are heavily based on practice in Australia and as such may not be uniformly applicable to other healthcare systems. This should be better emphasized in the discussion. | Emphasis has been added in the Discussion to highlight this limitation [page 10 line 330 - 333]:
“Barriers and facilitators have been discussed in the context of a federally-funded healthcare system such as exists in Australia and thus the recommendations from this review will not be relevant for all international contexts.”
This focus on the Australian health system has also been emphasised in the abstract [page 1 in lines 27-29] “In this review, barriers and facilitators to the implementation of evidence-based lifestyle management in reference to PCOS.” Replaced by “In this review, barriers and facilitators to the implementation of evidence-based lifestyle management in reference to PCOS are discussed in the context of a federally-funded health system.”
And in the discussion [page 6 line 262] with “The barriers discussed below are mostly within the context of federally-funded healthcare systems. replaced by “The barriers discussed below are mostly within the context of federally-funded healthcare systems as exists in Australia. “ |
How were the studies selected for inclusion in Table 1-- How many were reviewed and excluded as this is not comprehensive? | For clarity the text has been updated to below [page 5 lines 100-102]: “A summary of the various aspects of lifestyle management interventions and their benefits on anthropometric, cardiovascular, metabolic, reproductive and psychological health, based on evidence from meta-analyses, is shown in Table 1.
The search strategy was also detailed in the text [page 5, lines 102 – 105]:
“Meta-analyses were identified using search terms “lifestyle” or “diet” or “exercise” and “PCOS” using PubMed, Scopus and the Cochrane database of systematic reviews, through expert referral and previous reviews with key publications selected for their relevance by first authors.”
The title of Table 1 has been updated to: “A summary of current evidence from meta-analyses on lifestyle management in PCOS”
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Regarding the role of healthcare professionals, you should note the following reference: A W Lin, E J Bergomi, J S Dollahite, J Sobal, K M Hoeger, M E Lujan, Trust in Physicians and Medical Experience Beliefs Differ Between Women With and Without Polycystic Ovary Syndrome, Journal of the Endocrine Society, Volume 2, Issue 9, September 2018, Pages 1001–1009, https://doi.org/10.1210/js.2018-00181
This concludes women with PCOS reported greater overall distrust in the PCP’s opinions and more arguments with their health care providers than women without PCOS, which may influence some of your recommendations | The healthcare professional section has been expanded to include the dissatisfaction with healthcare professionals experienced by women with PCOS [page 4, lines 186 – 191]:
“However, it should be noted women with PCOS have reported dissatisfaction with provision of care and support from primary care providers when compared to women without PCOS (32, 75). A 2018 study concluded that women with PCOS report overall greater distrust in the opinions of their primary care physicians and reportedly had more arguments with other healthcare professionals, compared to women without PCOS (75). This may impact the ability of PCOS care providers to effectively implement lifestyle management.”
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Reviewer 2 Report
The article seeks to review lifestyle management in PCOS, specifically the barriers and facilitators to the implementation of lifestyle management. It would be useful to have the paper in double spaced format to make editing and review easier. The authors review the aetiology of PCOS, the link with obesity, and focus on the non-pharmacological management. The various lifestyle interventions (diet, exercise, behavioural) are discussed, as is the role of each different care provider. Table 1 includes a summary of the current evidence informing lifestyle management in PCOS, and whilst there is significant heterogeneity in the studies, it is a useful summary of the current evidence. The second part of the paper discusses both the barriers and facilitators to implementing lifestyle management.
The paper is relevant and timely given that PCOS is a common condition, obesity is becoming an ever growing burden, and lifestyle interventions have a proven benefit.
The paper is well written and thoroughly referenced, and I do not recommend any changes.
Author Response
Dear reviewer 2 and editor,
Thank you for the constructive feedback. Please see below our response to your comments and suggestions:
Comments and suggestions | Responses |
Reviewer 2 | |
The article seeks to review lifestyle management in PCOS, specifically the barriers and facilitators to the implementation of lifestyle management. It would be useful to have the paper in double spaced format to make editing and review easier.
| The text has been reformatted with double-spacing. |
The authors review the aetiology of PCOS, the link with obesity, and focus on the non-pharmacological management. The various lifestyle interventions (diet, exercise, behavioural) are discussed, as is the role of each different care provider. Table 1 includes a summary of the current evidence informing lifestyle management in PCOS, and whilst there is significant heterogeneity in the studies, it is a useful summary of the current evidence. | Thank you. |
The second part of the paper discusses both the barriers and facilitators to implementing lifestyle management. The paper is relevant and timely given that PCOS is a common condition, obesity is becoming an ever growing burden, and lifestyle interventions have a proven benefit. The paper is well written and thoroughly referenced, and I do not recommend any changes.
| Thank you. |