Next Article in Journal
Evaluation of Performance, Nitrogen Metabolism and Tissue Composition in Barrows Fed an n-3 PUFA-Rich Diet
Previous Article in Journal
Metatranscriptomic Analysis of Sub-Acute Ruminal Acidosis in Beef Cattle
Article Menu
Issue 5 (May) cover image

Export Article

Open AccessArticle

Comparative Analysis of the aquaporin Gene Family in 12 Fish Species

1,* and 2
1
Institute of Life Sciences, Jiangsu University, Zhenjiang 212013, China
2
Corporation of Lvdou Biopharmaceuticals, Binzhou 256600, China
*
Author to whom correspondence should be addressed.
Animals 2019, 9(5), 233; https://doi.org/10.3390/ani9050233
Received: 17 April 2019 / Revised: 10 May 2019 / Accepted: 11 May 2019 / Published: 13 May 2019
(This article belongs to the Section Animal Genetics and Genomics)
  |  
PDF [4343 KB, uploaded 13 May 2019]
  |  

Simple Summary

Aquaporins (Aqps) are a group of membrane proteins. In this study, 166 Aqp genes were identified in 12 fish species. Gene organization, motif distribution, recombination, and selection pressure were performed to investigate their evolutionary characteristics. In addition, expression profiles of Aqps were also examined under pathogens infection and organophosphorus pesticide stress. This study will provide a useful reference for further functional study.

Abstract

Aquaporins (Aqps) are a class of water channel proteins that play key roles in many physiological functions and cellular processes. Here, we analyzed 166 putative Aqp genes in 12 fish species and divided them into four groups. Gene organization and motif distribution analyses suggested potentially conserved functions in each group. Several recombination events were identified in some members, which accelerate their divergence in evolution. Furthermore, a few positive selection sites were identified, and mutations at these sites could alter the stability of Aqp proteins. In addition, expression profiles of some Aqp genes under pathogen infection and organophosphorus pesticide stress were also investigated. The result implied that several Aqp genes may affect different immune responses and osmoregulation. This study provides a comparative analysis of the fish Aqp gene family to facilitate further functional analyses. View Full-Text
Keywords: intragenic recombination; evolution; selective pressure; expression; organophosphorus pesticide intragenic recombination; evolution; selective pressure; expression; organophosphorus pesticide
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

Supplementary material

SciFeed

Share & Cite This Article

MDPI and ACS Style

Cao, J.; Shi, F. Comparative Analysis of the aquaporin Gene Family in 12 Fish Species. Animals 2019, 9, 233.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Animals EISSN 2076-2615 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top