Comparative Study of Classical and Alternative Therapy in Dogs with Allergies
Abstract
:Simple Summary
Abstract
1. Introduction
2. Materials and Methods
2.1. Dogs
2.2. Evaluation of Clinical Parameters
2.3. Diagnostics and Treatment Protocol
2.4. Statistical Evaluation
3. Results
3.1. The First Observed Group of Dogs
3.2. Clinicopathological Abnormalities
3.3. The Second Observed Group of Dogs
3.4. Clinicopathological Abnormalities
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Data Availability Statement
Conflicts of Interest
References
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Group 1 | Group 2 | |||||
---|---|---|---|---|---|---|
Breed | Age (Years) | Gender | Breed | Age (Years) | Gender | |
1 | Dogue de Bordeaux | 5 | F | Crossbreed dog | 5 | F |
2 | Chihuahua | 2 | F | Magyar Vizsla | 5 | M |
3 | Boxer | 8 | F | French Bulldog | 5 | M |
4 | German Shepherd | 9 | M | Pug | 3 | F |
5 | Maltese dog | 5 | M | Labrador retriever | 10 | M |
6 | Yorkshire Terrier | 6 | F | Schnauzer dog | 8 | M |
7 | Crossbreed dog | 9 | M | Crossbreed dog | 8 | F |
Dog | Clinical Symptoms before Therapy | Phytotherapy | Condition after Therapy |
---|---|---|---|
1 | Erythema and alopecia of the abdomen and limbs, pruritus, and nasal discharge | Silybum marianum | Without clinical symptoms |
2 | Erythema and alopecia of the abdomen and pruritus | Silybum marianum | Without clinical symptoms |
3 | Erythema in the axillae and pruritus | Curcuma longa | Alleviated pruritic condition |
4 | Erythema in the axillae and abdomen and pododermatitis | Pleurotus ostreatus | Without erythema and alleviated pododermatitis |
5 | Pruritus of mouth, axillae, abdomen, and limbs | Glycyrrhiza glabra | Alleviated pruritic condition |
6 | Pruritus around eyes and ears and nasal discharge | Silybum marianum | Without clinical symptoms |
7 | Pruritus of mouth and pododermatitis | Pleurotus ostreatus | Without clinical symptoms |
Dog | Ery 5.65–8.87 × 1012/L | Leu 5.05–16.76 × 109/L | Neu 2.00–12.00 × 109/L | Lym 0.50–4.90 × 109/L | Eos 0.10–1.49 × 109/L |
---|---|---|---|---|---|
B/A | B/A | B/A | B/A | B/A | |
1 | 5.73/5.78 | 15.46/10.72 | 9.55/8.03 | 2.65/2.12 | * 1.92/1.35 |
2 | 6.82/7.09 | * 16.93/10.22 | 10.12/7.98 | 3.34/3.02 | * 1.65/0.75 |
3 | 7.38/7.78 | 14.45/9.18 | 5.00/3.98 | 4.20/4.34 | * 1.55/0.81 |
4 | 5.35/5.68 | * 17.39/11.39 | * 14.15/12.00 | 0.52/0.70 | * 1.77/0.89 |
5 | 7.56/8.14 | 13.78/11.29 | 10.56/9.03 | 2.56/2.83 | * 1.89/1.11 |
6 | 5.23/5.66 | 10.59/8.00 | 8.00/6.73 | 2.35/2.82 | 1.29/0.57 |
7 | 5.65/5.85 | * 16.98/10.35 | * 12.52/11.22 | 0.50/0.52 | * 1.95/0.97 |
Dog | ALT 10–125 U/L | ALP 23–212 U/L | AMS 500–1500 U/L | LPS 200–1800 U/L | TC 110–320 mg/dL | BUN 7–27 mg/dL | CREA 0.5–1.8 mg/dL |
---|---|---|---|---|---|---|---|
B/A | B/A | B/A | B/A | B/A | B/A | B/A | |
1 | 13/20 | 76/82 | 822/850 | 1713/1618 | 121/119 | 12/10 | 1.5/1.2 |
2 | 45/41 | 50/64 | * 1520/980 | 205/201 | 41/44 | 8.2/7.9 | 1.3/1.1 |
3 | 81/85 | * 254/155 | 692/690 | 1560/1553 | 210/240 | * 32.2/26.1 | 0.99/0.62 |
4 | * 144/98 | * 352/191 | * 1700/1190 | * 1905/1450 | 256/283 | 15.6/13.4 | 0.8/0.7 |
5 | 78/76 | 210/98 | 1490/1325 | 1470/1426 | 265/268 | 14/12 | 1.6/1.5 |
6 | * 128/79 | 165/72 | 812/865 | 1786/1245 | 196/194 | 21/20 | 0.7/0.5 |
7 | * 132/89 | * 226/89 | * 1674/1167 | * 1952/1337 | 220/260 | 26/16 | 1.7/1.5 |
Dog | Clinical Symptoms before Therapy | Therapy | Status after Therapy |
---|---|---|---|
1 | Otitis externa, pododermatitis | ATB and Prednisolone | Without clinical symptoms |
2 | Pruritus of abdomen | Cytopoint and Prednisolone | Alleviated pruritic condition |
3 | Pruritus of eyes, mouth and anus, otitis externa | Apoquel, ATB, and Prednisolone | Ongoing therapy |
4 | Pododermatitis, pruritus of mouth and anus | Cytopoint, ATB, Prednisolone | Ongoing therapy |
5 | Otitis externa, pododermatitis, pruritus of abdomen, axillae, and limbs | Apoquel, ATB, and Prednisolone | Ongoing therapy |
6 | Pruritus of mouth and abdomen | Apoquel, ATB, and Prednisolone | Ongoing therapy |
7 | Pruritus of mouth, eyes, nasal discharge | ATB and Prednisolone | Without clinical symptoms |
Ery 5.65–8.87 ×1012/L | Leu 5.05–16.76 ×109/L | Neu 2.00–12.00 ×109/L | Lym 0.50–4.90 ×109/L | Eos 0.10–1.49 ×109/L | |
---|---|---|---|---|---|
Dog | B/A | B/A | B/A | B/A | B/A |
1 | 5.69/5.72 | 8.05/6.02 | 3.06/2.66 | 1.30/1.35 | * 1.58/1.47 |
2 | 6.25/6.41 | 9.25/6.12 | 7.36/6.93 | 2.35/2.14 | * 1.74/1.21 |
3 | 6.48/6.7 | 12.48/7.5 | 6.42/6.18 | 4.32/3.92 | 1.03/0.98 |
4 | 7.35/7.40 | 10.56/9.2 | 6.0/5.7 | 3.56/5.13 | * 1.95/1.54 * |
5 | 5.73/5.61 | 13.24/8.3 | 10.94/10.13 | 1.39/1.26 | 0.34/0.25 |
6 | 5.65/5.64 | 16.54/9.16 | 11.03/10.76 | 1.52/1.02 | * 1.67/0.93 |
7 | 6.21/5.79 | * 17.24/16.12 | * 13.54/11.25 | 0.52/0.59 | * 1.56/1.50 * |
Dog | ALT 10–125 U/L | ALP 23–212 U/L | AMS 500–1500 U/L | LPS 200–1800 U/L | TC 110–320 mg/dL | BUN 2.5–9.6 mmol/L | CREA 44–159 µmol/L |
---|---|---|---|---|---|---|---|
B/A | B/A | B/A | B/A | B/A | B/A | B/A | |
1 | 99/38 | 114/222 * | * 1540/1322 | * 1850/1970* | 258/275 | 8.6/9.8 * | 56/58 |
2 | 85/79 | 32/52 | * 1600/1420 | * 1850/1775 | 155/158 | 2.5/3.8 | 89/81 |
3 | 52/56 | * 286/282* | * 1746/1658* | 462/493 | 262/271 | 6.9/9.1 | 144/165 * |
4 | 33/41 | * 258/293* | 1418/1324 | 843/865 | 158/190 | 8.9/8.6 | 132/129 |
5 | 55/93 | 149/305 * | 934/955 | 1266/1178 | 255/283 | * 9.9/9.1 | * 172/135 |
6 | * 131/98 | * 252/394* | * 2336/2816* | * 1976/2038* | 253/263 | 2.4/2.1 | 155/183 * |
7 | * 141/18 | * 453/458* | * 1825/1454 | 1739/1952 * | 239/293 | 5.6/6.2 | 142/186 * |
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Micháľová, A.; Takáčová, M.; Karasová, M.; Kunay, L.; Grelová, S.; Fialkovičová, M. Comparative Study of Classical and Alternative Therapy in Dogs with Allergies. Animals 2022, 12, 1832. https://doi.org/10.3390/ani12141832
Micháľová A, Takáčová M, Karasová M, Kunay L, Grelová S, Fialkovičová M. Comparative Study of Classical and Alternative Therapy in Dogs with Allergies. Animals. 2022; 12(14):1832. https://doi.org/10.3390/ani12141832
Chicago/Turabian StyleMicháľová, Alena, Martina Takáčová, Martina Karasová, Lukáš Kunay, Simona Grelová, and Mária Fialkovičová. 2022. "Comparative Study of Classical and Alternative Therapy in Dogs with Allergies" Animals 12, no. 14: 1832. https://doi.org/10.3390/ani12141832