Antimicrobial Resistance and Genetic Lineages of Staphylococcus aureus from Wild Rodents: First Report of mecC-Positive Methicillin-Resistant S. aureus (MRSA) in Portugal
Abstract
:Simple Summary
Abstract
1. Introduction
2. Materials and Methods
2.1. Samples and Bacterial Isolates
2.2. Antimicrobial Susceptibility Testing
2.3. Antimicrobial Resistance and Virulence Genes
2.4. Molecular Typing
3. Results
4. Discussion
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Data Availability Statement
Conflicts of Interest
References
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Isolate | Host Species | Antimicrobial Resistance | Virulence Factors | Molecular Typing | |||||
---|---|---|---|---|---|---|---|---|---|
Phenotype | Genotype | IEC System | Other Genes | ST (CC) | spa | agr | SCCmec | ||
VS2808 | Rattus rattus | PEN, FOX | mecC, blaZ-SCCmecXI | Type E | - | 1945 (130) | t1535 | III | XI |
VS2809 | Rattus rattus | PEN, FOX | mecC, blaZ-SCCmecXI | Type E | - | 1945 (130) | t1535 | III | XI |
VS2810 | Rattus norvegicus | PEN, FOX | mecC, blaZ-SCCmecXI | Type E | - | 1945 (130) | t1535 | III | XI |
VS2811 | Rattus rattus | PEN, FOX, CIP, ERY | mecA, blaZ | - | hlb, hld | 22 (22) | t747 | I | N.T. |
VS2812 | Rattus rattus | PEN, FOX, CIP, CN, KAN, ERY, CD | mecA, blaZ, aph(3′)-IIIa, ermA | Type A | hlb, hld | 36 (30) | t018 | I | N.T. |
VS2813 | Rattus rattus | PEN, FOX, CIP | mecA, blaZ | - | hlb, hld | 22 (22) | t747 | I | N.T. |
VS2814 | Rattus norvegicus | Susceptible | - | - | hlb, hld | 1094 | t516 | I | - |
VS2815 | Rattus norvegicus | Susceptible | - | - | hlb, hld | 1094 | t516 | I | - |
VS2816 | Rattus norvegicus | PEN | blaZ | - | hlb, hld | 1094 | t516 | I | - |
VS2817 | Rattus rattus | Susceptible | - | - | hlb, hld | 1094 | t516 | I | - |
VS2818 | Rattus norvegicus | Susceptible | - | - | hlb, hld | 1094 | t516 | I | - |
VS2819 | Rattus rattus | Susceptible | - | - | hlb, hld | 1094 | t516 | I | - |
VS2820 | Rattus norvegicus | Susceptible | - | - | hlb, hld | 1094 | t516 | I | - |
VS2821 | Rattus norvegicus | Susceptible | - | - | hlb, hld | 130 | t843 | III | - |
VS2822 | Rattus norvegicus | Susceptible | - | - | hlb, hld | 130 | t843 | III | - |
VS2823 | Rattus norvegicus | Susceptible | - | - | hlb, hld | 130 | t843 | III | - |
VS2824 | Rattus norvegicus | Susceptible | - | scn | hld | 130 | t843 | III | - |
VS2825 | Rattus norvegicus | Susceptible | - | - | hlb, hld | 130 | t843 | III | - |
VS2826 | Rattus rattus | Susceptible | - | - | hlb, hld | 130 | t3256 | III | - |
VS2827 | Rattus norvegicus | Susceptible | - | - | - | 130 | t3256 | N.T. | - |
VS2828 | Rattus norvegicus | Susceptible | - | - | hlb, hld | 1245 | t843 | III | - |
VS2829 | Rattus rattus | Susceptible | - | - | hlb, hld | 1245 | t843 | III | - |
VS2830 | Rattus norvegicus | PEN | blaZ | - | hld | 398 | t1451 | I | - |
VS2831 | Rattus norvegicus | PEN | blaZ | - | hld | 398 | t1451 | I | - |
VS2832 | Rattus norvegicus | PEN | blaZ | - | hld | 398 | t1451 | I | - |
VS2833 | Rattus norvegicus | Susceptible | - | - | hld | 398 | t571 | I | - |
VS2834 | Rattus rattus | Susceptible | - | Type C | hld | 5926 | t1451 | N.T. | - |
VS2835 | Rattus norvegicus | Susceptible | - | Type C | hld | 5926 | t1451 | I | - |
VS2836 | Rattus norvegicus | PEN | blaZ | Type E | hlb, hld | 1318 | t2078 | I | - |
VS2837 | Rattus norvegicus | Susceptible | - | - | hld | 8 (8) | t4608 | I | - |
VS2838 | Rattus norvegicus | Susceptible | - | - | hlb, hld | 8 (8) | t19688 | I | - |
VS2839 | Rattus norvegicus | Susceptible | - | - | hlb, hld | 8 (8) | t4608 | I | - |
VS2840 | Rattus norvegicus | Susceptible | - | - | hlb, hld | 6574 | t1535 | III | - |
VS2841 | Rattus norvegicus | Susceptible | - | - | hlb, hld | 6574 | t1535 | N.T. | - |
VS2842 | Rattus norvegicus | PEN | blaZ | - | hlb, hld | 34 (30) | t414 | N.T. | - |
VS2843 | Rattus rattus | Susceptible | - | - | hld | 6 (5) | t16615 | I | - |
VS2844 | Rattus rattus | Susceptible | - | - | hlb, hld | 5926 | t1451 | N.T. | - |
VS2845 | Rattus norvegicus | Susceptible | - | - | hlb, hld | 1290 (1) | t131 | I | - |
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Silva, V.; Gabriel, S.I.; Borrego, S.B.; Tejedor-Junco, M.T.; Manageiro, V.; Ferreira, E.; Reis, L.; Caniça, M.; Capelo, J.L.; Igrejas, G.; et al. Antimicrobial Resistance and Genetic Lineages of Staphylococcus aureus from Wild Rodents: First Report of mecC-Positive Methicillin-Resistant S. aureus (MRSA) in Portugal. Animals 2021, 11, 1537. https://doi.org/10.3390/ani11061537
Silva V, Gabriel SI, Borrego SB, Tejedor-Junco MT, Manageiro V, Ferreira E, Reis L, Caniça M, Capelo JL, Igrejas G, et al. Antimicrobial Resistance and Genetic Lineages of Staphylococcus aureus from Wild Rodents: First Report of mecC-Positive Methicillin-Resistant S. aureus (MRSA) in Portugal. Animals. 2021; 11(6):1537. https://doi.org/10.3390/ani11061537
Chicago/Turabian StyleSilva, Vanessa, Sofia I. Gabriel, Sofia B. Borrego, Maria Teresa Tejedor-Junco, Vera Manageiro, Eugénia Ferreira, Lígia Reis, Manuela Caniça, José L. Capelo, Gilberto Igrejas, and et al. 2021. "Antimicrobial Resistance and Genetic Lineages of Staphylococcus aureus from Wild Rodents: First Report of mecC-Positive Methicillin-Resistant S. aureus (MRSA) in Portugal" Animals 11, no. 6: 1537. https://doi.org/10.3390/ani11061537