Regeneration during Obesity: An Impaired Homeostasis
Department of Molecular Medicine, Faculty of Medicine, Laval University, Quebec City, QC G1V 0A6, Canada
Functional Genomics Laboratory, Endocrinology and Nephrology Axis, CHU de Québec-Université Laval Research Center, Quebec City, QC G1V 4G2, Canada
Author to whom correspondence should be addressed.
Received: 13 November 2020
Revised: 4 December 2020
Accepted: 7 December 2020
Published: 9 December 2020
Regeneration represents the biological processes that allow cells and tissues to renew and develop. During obesity, a variety of changes and reactions are seen. This includes inflammation and metabolic disorders. These obesity-induced changes do impact the regeneration processes. Such impacts that obesity has on regeneration would affect tissues and organs development and would also have consequences on the outcomes of therapies that depend on cells regeneration (such as burns, radiotherapy and leukemia) given to patients suffering from obesity. Therefore, a particular attention should be given to patients suffering from obesity in biological, therapeutic and clinical contexts that depend on regeneration ability.