Rhodotorula kratochvilovae CCY 20-2-26—The Source of Multifunctional Metabolites

Byrtusová, Dana; Szotkowski, Martin; Kurowska, Klára; Shapaval, Volha; Márová, Ivana

doi:10.3390/microorganisms9061280

Open AccessArticle

Rhodotorula kratochvilovae CCY 20-2-26—The Source of Multifunctional Metabolites

by

Dana Byrtusová

^1,2

,

Martin Szotkowski

²,

Klára Kurowska

²,

Volha Shapaval

¹

and

Ivana Márová

^2,*

¹

Faculty of Science and Technology, Norwegian University of Life Sciences, P.O. Box 5003, 1432 Ås, Norway

²

Faculty of Chemistry, Brno University of Technology, Purkyňova 464/118, 612 00 Brno, Czech Republic

^*

Author to whom correspondence should be addressed.

Microorganisms 2021, 9(6), 1280; https://doi.org/10.3390/microorganisms9061280

Submission received: 29 April 2021 / Revised: 1 June 2021 / Accepted: 8 June 2021 / Published: 11 June 2021

(This article belongs to the Special Issue Microbial Stress Response as a Tool for Biotechnology)

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Abstract

Multifunctional biomass is able to provide more than one valuable product, and thus, it is attractive in the field of microbial biotechnology due to its economic feasibility. Carotenogenic yeasts are effective microbial factories for the biosynthesis of a broad spectrum of biomolecules that can be used in the food and feed industry and the pharmaceutical industry, as well as a source of biofuels. In the study, we examined the effect of different nitrogen sources, carbon sources and CN ratios on the co-production of intracellular lipids, carotenoids, β–glucans and extracellular glycolipids. Yeast strain R. kratochvilovae CCY 20-2-26 was identified as the best co-producer of lipids (66.7 ± 1.5% of DCW), exoglycolipids (2.42 ± 0.08 g/L), β-glucan (11.33 ± 1.34% of DCW) and carotenoids (1.35 ± 0.11 mg/g), with a biomass content of 15.2 ± 0.8 g/L, by using the synthetic medium with potassium nitrate and mannose as a carbon source. It was shown that an increased C/N ratio positively affected the biomass yield and production of lipids and β-glucans.

Keywords: Rhodotorula kratochvilovae; lipids; extracellular glycolipids; carotenoids; β-glucan

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MDPI and ACS Style

Byrtusová, D.; Szotkowski, M.; Kurowska, K.; Shapaval, V.; Márová, I. Rhodotorula kratochvilovae CCY 20-2-26—The Source of Multifunctional Metabolites. Microorganisms 2021, 9, 1280. https://doi.org/10.3390/microorganisms9061280

AMA Style

Byrtusová D, Szotkowski M, Kurowska K, Shapaval V, Márová I. Rhodotorula kratochvilovae CCY 20-2-26—The Source of Multifunctional Metabolites. Microorganisms. 2021; 9(6):1280. https://doi.org/10.3390/microorganisms9061280

Chicago/Turabian Style

Byrtusová, Dana, Martin Szotkowski, Klára Kurowska, Volha Shapaval, and Ivana Márová. 2021. "Rhodotorula kratochvilovae CCY 20-2-26—The Source of Multifunctional Metabolites" Microorganisms 9, no. 6: 1280. https://doi.org/10.3390/microorganisms9061280

APA Style

Byrtusová, D., Szotkowski, M., Kurowska, K., Shapaval, V., & Márová, I. (2021). Rhodotorula kratochvilovae CCY 20-2-26—The Source of Multifunctional Metabolites. Microorganisms, 9(6), 1280. https://doi.org/10.3390/microorganisms9061280

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Rhodotorula kratochvilovae CCY 20-2-26—The Source of Multifunctional Metabolites

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