Next Article in Journal
Psychrophilic Bacterial Phosphate-Biofertilizers: A Novel Extremophile for Sustainable Crop Production under Cold Environment
Next Article in Special Issue
Safety Assessment of Lactiplantibacillus plantarum TWK10 Based on Whole-Genome Sequencing, Phenotypic, and Oral Toxicity Analysis
Previous Article in Journal
Lactobacillus delbrueckii CRL 581 Differentially Modulates TLR3-Triggered Antiviral Innate Immune Response in Intestinal Epithelial Cells and Macrophages
Previous Article in Special Issue
Lactic Acid Bacteria Exert a Hepatoprotective Effect against Ethanol-Induced Liver Injury in HepG2 Cells
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
Microorganisms
Volume 9
Issue 12
10.3390/microorganisms9122450
microorganisms-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Article

Safety Evaluation of Weissella cibaria JW15 by Phenotypic and Genotypic Property Analysis

by
Ye-Ji Jang
,
Hee-Min Gwon
,
Woo-Soo Jeong
,
Soo-Hwan Yeo
and
So-Young Kim
*
Fermented and Processed Food Science Division, Department of Agrofood Resources, National Institute of Agricultural Science, Rural Development Administration, Wanju 55365, Korea
*
Author to whom correspondence should be addressed.
Microorganisms 2021, 9(12), 2450; https://doi.org/10.3390/microorganisms9122450
Submission received: 26 October 2021 / Revised: 23 November 2021 / Accepted: 23 November 2021 / Published: 27 November 2021
(This article belongs to the Special Issue Benefical Properties and Safety of Lactic Acid Bacteria)
Browse Figures
Review Reports Versions Notes

Abstract

Weissella cibaria is one of the bacteria in charge of the initial fermentation of kimchi and has beneficial effects such as immune-modulating, antagonistic, and antioxidant activities. In our study, we aimed to estimate the safety of W. cibaria JW15 for the use of probiotics according to international standards based on phenotypic (antibiotic resistance, hemolysis, and toxic metabolite production) and genotypic analysis (virulence genes including antibiotic resistance genes). The results of the safety assessment on W. cibaria JW15 were as follows; (1) antibiotic resistance genes (ARGs) (kanamycin and vancomycin etc.) were intrinsic characteristics; (2) There were no acquired virulence genes including Cytolysin (cylA), aggregation substance (asa1), Hyaluronidase (hyl), and Gelatinase (gelE); (3) this strain also lacked β-hemolysis and the production of toxic metabolites (D-lactate and bile salt deconjugation). Consequently, W. cibaria JW15 is expected to be applied as a functional food ingredient in the food market.
Keywords: Weissella cibaria; safety; ARGs; virulence gene; toxic metabolite Weissella cibaria; safety; ARGs; virulence gene; toxic metabolite

Share and Cite

MDPI and ACS Style

Jang, Y.-J.; Gwon, H.-M.; Jeong, W.-S.; Yeo, S.-H.; Kim, S.-Y. Safety Evaluation of Weissella cibaria JW15 by Phenotypic and Genotypic Property Analysis. Microorganisms 2021, 9, 2450. https://doi.org/10.3390/microorganisms9122450

AMA Style

Jang Y-J, Gwon H-M, Jeong W-S, Yeo S-H, Kim S-Y. Safety Evaluation of Weissella cibaria JW15 by Phenotypic and Genotypic Property Analysis. Microorganisms. 2021; 9(12):2450. https://doi.org/10.3390/microorganisms9122450

Chicago/Turabian Style

Jang, Ye-Ji, Hee-Min Gwon, Woo-Soo Jeong, Soo-Hwan Yeo, and So-Young Kim. 2021. "Safety Evaluation of Weissella cibaria JW15 by Phenotypic and Genotypic Property Analysis" Microorganisms 9, no. 12: 2450. https://doi.org/10.3390/microorganisms9122450

APA Style

Jang, Y.-J., Gwon, H.-M., Jeong, W.-S., Yeo, S.-H., & Kim, S.-Y. (2021). Safety Evaluation of Weissella cibaria JW15 by Phenotypic and Genotypic Property Analysis. Microorganisms, 9(12), 2450. https://doi.org/10.3390/microorganisms9122450

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

Article Metrics

Back to TopTop