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Article
Peer-Review Record

Spread of Carbapenem-Resistant Gram-Negatives and Candida auris during the COVID-19 Pandemic in Critically Ill Patients: One Step Back in Antimicrobial Stewardship?

Microorganisms 2021, 9(1), 95; https://doi.org/10.3390/microorganisms9010095
by Laura Magnasco 1,*, Malgorzata Mikulska 1,2, Daniele Roberto Giacobbe 1,2, Lucia Taramasso 1, Antonio Vena 1, Chiara Dentone 1, Silvia Dettori 2, Stefania Tutino 2, Laura Labate 2, Vincenzo Di Pilato 3, Francesca Crea 4, Erika Coppo 3,4, Giulia Codda 3, Chiara Robba 5, Lorenzo Ball 3,5, Nicolo’ Patroniti 3,5, Anna Marchese 3,4, Paolo Pelosi 3,5 and Matteo Bassetti 1,2
Reviewer 1: Anonymous
Reviewer 2:
Microorganisms 2021, 9(1), 95; https://doi.org/10.3390/microorganisms9010095
Submission received: 12 December 2020 / Revised: 26 December 2020 / Accepted: 29 December 2020 / Published: 3 January 2021
(This article belongs to the Section Antimicrobial Agents and Resistance)

Round 1

Reviewer 1 Report

Discussion, beginning:

I would like to see CRPA explained here. Also, why it is not said that CR-Kp has been also tested in this study? 

Line 140 - maybe addition to "baseline" needed: "at baseline level"? 

Grammar: 

line 49 - "form" - change to "from"

 

 

 

Author Response

Please see the attachment.

Author Response File: Author Response.pdf

Reviewer 2 Report

Antibiotic resistance is a growing global menace. It has been intensified and complicated by the fight against COVID-19. In this manuscript, Magnasco and coworkers report the colonization/infection of the drug-resistance pathogen between COVID-19 patients admitted to the ICU. This work will be of broad interest to readers of Microorganisms journal. However, some items need to be addressed before publication.

  1. The primary concern is Table 1, which outlines the data of 14 patients. However, only 12 patients were colonized or infected with CRPA, C.auris, or CR-Kp in this study (Line 115). The authors must clarify the discrepancy. Besides, it would be nice if authors can mark which patient is from the 12-bed ICU in the table.
  2. P. aeruginosa and C.auris are not italicized in the result section and should be correct.
  3. Line 265-271: Conflicts of Interest is incomplete. 

Author Response

Please see attached file.

Author Response File: Author Response.pdf

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