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Open AccessArticle

Janthinobacterium CG23_2: Comparative Genome Analysis Reveals Enhanced Environmental Sensing and Transcriptional Regulation for Adaptation to Life in an Antarctic Supraglacial Stream

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Center for Biofilm Engineering, Montana State University, Bozeman, MT 59717, USA
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Department of Chemical & Biological Engineering, Montana State University, Bozeman, MT 59715, USA
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Department of Microbiology & Immunology, Montana State University, Bozeman, MT 59717, USA
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School of Computing, College of Computing & Digital Media, DePaul University, Chicago, IL 60604, USA
*
Author to whom correspondence should be addressed.
Microorganisms 2019, 7(10), 454; https://doi.org/10.3390/microorganisms7100454
Received: 25 September 2019 / Revised: 12 October 2019 / Accepted: 14 October 2019 / Published: 15 October 2019
(This article belongs to the Special Issue Microbial Evolution of Extremophiles)
As many bacteria detected in Antarctic environments are neither true psychrophiles nor endemic species, their proliferation in spite of environmental extremes gives rise to genome adaptations. Janthinobacterium sp. CG23_2 is a bacterial isolate from the Cotton Glacier stream, Antarctica. To understand how Janthinobacterium sp. CG23_2 has adapted to its environment, we investigated its genomic traits in comparison to genomes of 35 published Janthinobacterium species. While we hypothesized that genome shrinkage and specialization to narrow ecological niches would be energetically favorable for dwelling in an ephemeral Antarctic stream, the genome of Janthinobacterium sp. CG23_2 was on average 1.7 ± 0.6 Mb larger and predicted 1411 ± 499 more coding sequences compared to the other Janthinobacterium spp. Putatively identified horizontal gene transfer events contributed 0.92 Mb to the genome size expansion of Janthinobacterium sp. CG23_2. Genes with high copy numbers in the species-specific accessory genome of Janthinobacterium sp. CG23_2 were associated with environmental sensing, locomotion, response and transcriptional regulation, stress response, and mobile elements—functional categories which also showed molecular adaptation to cold. Our data suggest that genome plasticity and the abundant complementary genes for sensing and responding to the extracellular environment supported the adaptation of Janthinobacterium sp. CG23_2 to this extreme environment. View Full-Text
Keywords: Janthinobacterium; comparative genomics; horizontal gene transfer; cold adaptation; environmental sensing Janthinobacterium; comparative genomics; horizontal gene transfer; cold adaptation; environmental sensing
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MDPI and ACS Style

Dieser, M.; Smith, H.J.; Ramaraj, T.; Foreman, C.M. Janthinobacterium CG23_2: Comparative Genome Analysis Reveals Enhanced Environmental Sensing and Transcriptional Regulation for Adaptation to Life in an Antarctic Supraglacial Stream. Microorganisms 2019, 7, 454.

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