Next Article in Journal
The Influence of Playing Position and Contextual Factors on Soccer Players’ Match Differential Ratings of Perceived Exertion: A Preliminary Investigation
Previous Article in Journal
Topical and Ingested Cooling Methodologies for Endurance Exercise Performance in the Heat
Previous Article in Special Issue
The Three-Month Effects of a Ketogenic Diet on Body Composition, Blood Parameters, and Performance Metrics in CrossFit Trainees: A Pilot Study
Article Menu
Issue 1 (March) cover image

Export Article

Open AccessReview

Nutrition and Supplementation Considerations to Limit Endotoxemia When Exercising in the Heat

1
School of Health, Medical and Applied Sciences, Central Queensland University, Cairns 4870, Australia
2
School of Health, Medical and Applied Sciences, Central Queensland University, Adelaide 5034, Australia
*
Author to whom correspondence should be addressed.
Sports 2018, 6(1), 12; https://doi.org/10.3390/sports6010012
Received: 19 December 2017 / Revised: 25 January 2018 / Accepted: 31 January 2018 / Published: 6 February 2018
(This article belongs to the Special Issue Clinical and Sports Nutrition)
  |  
PDF [482 KB, uploaded 6 February 2018]
  |  

Abstract

Exercise-induced heat production is further elevated by exercise performed in hot conditions and this can subsequently impact inflammation, and gastrointestinal (GI) health. Implementing nutrition and supplementation strategies under these conditions may support the hyperthermic response, the systemic inflammatory response, GI permeability and integrity, and exercise performance. Therefore, the aim of this brief review is to explore athletes’ inflammatory response of two key biomarkers, lipopolysaccharide (LPS), and interleukin-6 (IL-6), and provide nutrition and supplementation recommendations when exercising in hot conditions. There is emerging evidence that probiotics, glutamine, and vitamin C can preserve GI integrity, which may improve performance during exercise in the heat. Glucose rich food when consumed with water, before and during exercise in the heat, also appear to limit endotoxemia, preserve GI integrity, and reduce the incidence of GI disturbances compared with water alone. The use of non-steroidal anti-inflammatory drugs (NSAIDs) may compromise GI integrity and this may result in greater leakage of endotoxins during long duration exercise in the heat. Further work is required to elucidate the impact of nutrition and supplementation strategies, in particular the use of NSAIDs, when exercising in the heat. View Full-Text
Keywords: heat stress; inflammation; cytokines; hydration; gastrointestinal permeability heat stress; inflammation; cytokines; hydration; gastrointestinal permeability
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
SciFeed

Share & Cite This Article

MDPI and ACS Style

Guy, J.H.; Vincent, G.E. Nutrition and Supplementation Considerations to Limit Endotoxemia When Exercising in the Heat. Sports 2018, 6, 12.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Sports EISSN 2075-4663 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top