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Article

In Vivo Verification of Treatment Source Dwell Times in Brachytherapy of Postoperative Endometrial Carcinoma: A Feasibility Study

1
Fonaments Clínics Department, University of Barcelona, 08036 Barcelona, Spain
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Radiation Oncology Department, Hospital Clínic Universitari, 08036 Barcelona, Spain
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Radiation Oncology Department, Hospital Universitari i Politècnic La Fe, 46026 Valencia, Spain
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Radiation Oncology Department, Hospital Clinica Benidorm, 03501 Alicante, Spain
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IRIMED, IIS-La Fe-Universitat de Valencia (UV), 46100 Burjassot, Spain
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Mathematics Department, Autonomous University of Barcelona, 08193 Bellatera, Spain
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NU-RISE LDA, PCI–Creative Science Park, 3830-352 Ilhavo, Portugal
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U.O.C. Radioterapia Oncologica, Dipartimento di Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy
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Gynecologic Cancer Unit, Hospital Clínic Universitari, 08036 Barcelona, Spain
*
Author to whom correspondence should be addressed.
Academic Editor: Eleanor E. R. Harris
J. Pers. Med. 2022, 12(6), 911; https://doi.org/10.3390/jpm12060911
Received: 30 March 2022 / Revised: 24 May 2022 / Accepted: 28 May 2022 / Published: 31 May 2022
(This article belongs to the Special Issue Application of Brachytherapy in Clinical Practice)
(1) Background: In brachytherapy, there are still many manual procedures that can cause adverse events which can be detected with in vivo dosimetry systems. Plastic scintillator dosimeters (PSD) have interesting properties to achieve this objective such as real-time reading, linearity, repeatability, and small size to fit inside brachytherapy catheters. The purpose of this study was to evaluate the performance of a PSD in postoperative endometrial brachytherapy in terms of source dwell time accuracy. (2) Methods: Measurements were carried out in a PMMA phantom to characterise the PSD. Patient measurements in 121 dwell positions were analysed to obtain the differences between planned and measured dwell times. (3) Results: The repeatability test showed a relative standard deviation below 1% for the measured dwell times. The relative standard deviation of the PSD sensitivity with accumulated absorbed dose was lower than 1.2%. The equipment operated linearly in total counts with respect to absorbed dose and also in count rate versus absorbed dose rate. The mean (standard deviation) of the absolute differences between planned and measured dwell times in patient treatments was 0.0 (0.2) seconds. (4) Conclusions: The PSD system is useful as a quality assurance tool for brachytherapy treatments. View Full-Text
Keywords: brachytherapy; endometrial carcinoma; treatment verification; in vivo dosimetry; plastic scintillator dosimeter brachytherapy; endometrial carcinoma; treatment verification; in vivo dosimetry; plastic scintillator dosimeter
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MDPI and ACS Style

Herreros, A.; Pérez-Calatayud, J.; Ballester, F.; Barrera-Gómez, J.; Abellana, R.; Melo, J.; Moutinho, L.; Tagliaferri, L.; Rovirosa, Á. In Vivo Verification of Treatment Source Dwell Times in Brachytherapy of Postoperative Endometrial Carcinoma: A Feasibility Study. J. Pers. Med. 2022, 12, 911. https://doi.org/10.3390/jpm12060911

AMA Style

Herreros A, Pérez-Calatayud J, Ballester F, Barrera-Gómez J, Abellana R, Melo J, Moutinho L, Tagliaferri L, Rovirosa Á. In Vivo Verification of Treatment Source Dwell Times in Brachytherapy of Postoperative Endometrial Carcinoma: A Feasibility Study. Journal of Personalized Medicine. 2022; 12(6):911. https://doi.org/10.3390/jpm12060911

Chicago/Turabian Style

Herreros, Antonio, José Pérez-Calatayud, Facundo Ballester, Jose Barrera-Gómez, Rosa Abellana, Joana Melo, Luis Moutinho, Luca Tagliaferri, and Ángeles Rovirosa. 2022. "In Vivo Verification of Treatment Source Dwell Times in Brachytherapy of Postoperative Endometrial Carcinoma: A Feasibility Study" Journal of Personalized Medicine 12, no. 6: 911. https://doi.org/10.3390/jpm12060911

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