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Article

Collaborative Approach to Reach Everyone with Familial Hypercholesterolemia: CARE-FH Protocol

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Heart and Vascular Institute, Geisinger, Danville, PA 17821, USA
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Genomic Medicine Institute, Geisinger, Danville, PA 17821, USA
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Department of Pediatrics, Geisinger, Danville, PA 17821, USA
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Department of Population Health Sciences, Geisinger, Danville, PA 17821, USA
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Department of Community Medicine, Geisinger, Danville, PA 17821, USA
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Department of Internal Medicine, Geisinger, Danville, PA 17821, USA
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Department of Translational Data Science and Informatics, Geisinger, Danville, PA 17821, USA
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Geisinger Commonwealth School of Medicine, Scranton, PA 18510, USA
*
Author to whom correspondence should be addressed.
Academic Editor: Nina Sperber
J. Pers. Med. 2022, 12(4), 606; https://doi.org/10.3390/jpm12040606
Received: 9 March 2022 / Revised: 29 March 2022 / Accepted: 6 April 2022 / Published: 9 April 2022
(This article belongs to the Special Issue Personalized Medicine: The Future of Health Care)
The Collaborative Approach to Reach Everyone with Familial Hypercholesterolemia (CARE-FH) study aims to improve diagnostic evaluation rates for FH at Geisinger, an integrated health delivery system. This clinical trial relies upon implementation science to transition the initial evaluation for FH into primary care, attempting to identify individuals prior to the onset of atherosclerotic cardiovascular disease events. The protocol for the CARE-FH study of this paper is available online. The first phase of the project focuses on trial design, including the development of implementation strategies to deploy evidence-based guidelines. The second phase will study the intervention, rolled out regionally to internal medicine, community medicine, and pediatric care clinicians using a stepped-wedge design, and analyzing data on diagnostic evaluation rates, and implementation, service, and health outcomes. View Full-Text
Keywords: familial hypercholesterolemia; prevention; primary care; implementation science; cholesterol screening familial hypercholesterolemia; prevention; primary care; implementation science; cholesterol screening
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MDPI and ACS Style

Jones, L.K.; Williams, M.S.; Ladd, I.G.; Cawley, D.; Ge, S.; Hao, J.; Hassen, D.; Hu, Y.; Kirchner, H.L.; Kobylinski, M.; Lesko, M.G.; Nelson, M.C.; Rahm, A.K.; Rolston, D.D.; Romagnoli, K.M.; Schubert, T.J.; Shuey, T.C.; Sturm, A.C.; Gidding, S.S. Collaborative Approach to Reach Everyone with Familial Hypercholesterolemia: CARE-FH Protocol. J. Pers. Med. 2022, 12, 606. https://doi.org/10.3390/jpm12040606

AMA Style

Jones LK, Williams MS, Ladd IG, Cawley D, Ge S, Hao J, Hassen D, Hu Y, Kirchner HL, Kobylinski M, Lesko MG, Nelson MC, Rahm AK, Rolston DD, Romagnoli KM, Schubert TJ, Shuey TC, Sturm AC, Gidding SS. Collaborative Approach to Reach Everyone with Familial Hypercholesterolemia: CARE-FH Protocol. Journal of Personalized Medicine. 2022; 12(4):606. https://doi.org/10.3390/jpm12040606

Chicago/Turabian Style

Jones, Laney K., Marc S. Williams, Ilene G. Ladd, Dylan Cawley, Shuping Ge, Jing Hao, Dina Hassen, Yirui Hu, H. L. Kirchner, Maria Kobylinski, Michael G. Lesko, Matthew C. Nelson, Alanna K. Rahm, David D. Rolston, Katrina M. Romagnoli, Tyler J. Schubert, Timothy C. Shuey, Amy C. Sturm, and Samuel S. Gidding. 2022. "Collaborative Approach to Reach Everyone with Familial Hypercholesterolemia: CARE-FH Protocol" Journal of Personalized Medicine 12, no. 4: 606. https://doi.org/10.3390/jpm12040606

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