Next Article in Journal
Gender-Specific Risk Factors for the Development of Retinal Changes in Children with Type 1 Diabetes
Previous Article in Journal
Depression Levels Influence the Rate of Asthma Exacerbations in Females
Article

Acceptability, Appropriateness, and Feasibility of Automated Screening Approaches and Family Communication Methods for Identification of Familial Hypercholesterolemia: Stakeholder Engagement Results from the IMPACT-FH Study

1
Genomic Medicine Institute, Geisinger, Danville, PA 17822, USA
2
The FH Foundation, Pasadena, CA 91101, USA
3
Department of Advertising, University of Florida, Gainesville, FL 33620, USA
4
Dartmouth Hitchcock Medical Center, Lebanon, NH 03756, USA
*
Author to whom correspondence should be addressed.
Academic Editor: Iftikhar J. Kullo
J. Pers. Med. 2021, 11(6), 587; https://doi.org/10.3390/jpm11060587
Received: 13 May 2021 / Revised: 8 June 2021 / Accepted: 15 June 2021 / Published: 21 June 2021
(This article belongs to the Special Issue Genomic Medicine for Cardiovascular Disease)
Guided by the Conceptual Model of Implementation Research, we explored the acceptability, appropriateness, and feasibility of: (1) automated screening approaches utilizing existing health data to identify those who require subsequent diagnostic evaluation for familial hypercholesterolemia (FH) and (2) family communication methods including chatbots and direct contact to communicate information about inherited risk for FH. Focus groups were conducted with 22 individuals with FH (2 groups) and 20 clinicians (3 groups). These were recorded, transcribed, and analyzed using deductive (coded to implementation outcomes) and inductive (themes based on focus group discussions) methods. All stakeholders described these initiatives as: (1) acceptable and appropriate to identify individuals with FH and communicate risk with at-risk relatives; and (2) feasible to implement in current practice. Stakeholders cited current initiatives, outside of FH (e.g., pneumonia protocols, colon cancer and breast cancer screenings), that gave them confidence for successful implementation. Stakeholders described perceived obstacles, such as nonfamiliarity with FH, that could hinder implementation and potential solutions to improve systematic uptake of these initiatives. Automated health data screening, chatbots, and direct contact approaches may be useful for patients and clinicians to improve FH diagnosis and cascade screening. View Full-Text
Keywords: familial hypercholesterolemia; identification; implementation outcomes; cascade screening; cascade testing; chatbots; direct contact familial hypercholesterolemia; identification; implementation outcomes; cascade screening; cascade testing; chatbots; direct contact
Show Figures

Figure 1

MDPI and ACS Style

Jones, L.K.; Walters, N.; Brangan, A.; Ahmed, C.D.; Gatusky, M.; Campbell-Salome, G.; Ladd, I.G.; Sheldon, A.; Gidding, S.S.; McGowan, M.P.; Rahm, A.K.; Sturm, A.C. Acceptability, Appropriateness, and Feasibility of Automated Screening Approaches and Family Communication Methods for Identification of Familial Hypercholesterolemia: Stakeholder Engagement Results from the IMPACT-FH Study. J. Pers. Med. 2021, 11, 587. https://doi.org/10.3390/jpm11060587

AMA Style

Jones LK, Walters N, Brangan A, Ahmed CD, Gatusky M, Campbell-Salome G, Ladd IG, Sheldon A, Gidding SS, McGowan MP, Rahm AK, Sturm AC. Acceptability, Appropriateness, and Feasibility of Automated Screening Approaches and Family Communication Methods for Identification of Familial Hypercholesterolemia: Stakeholder Engagement Results from the IMPACT-FH Study. Journal of Personalized Medicine. 2021; 11(6):587. https://doi.org/10.3390/jpm11060587

Chicago/Turabian Style

Jones, Laney K., Nicole Walters, Andrew Brangan, Catherine D. Ahmed, Michael Gatusky, Gemme Campbell-Salome, Ilene G. Ladd, Amanda Sheldon, Samuel S. Gidding, Mary P. McGowan, Alanna K. Rahm, and Amy C. Sturm 2021. "Acceptability, Appropriateness, and Feasibility of Automated Screening Approaches and Family Communication Methods for Identification of Familial Hypercholesterolemia: Stakeholder Engagement Results from the IMPACT-FH Study" Journal of Personalized Medicine 11, no. 6: 587. https://doi.org/10.3390/jpm11060587

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop