Next Article in Journal
Automated Machine Learning in Dentistry: A Narrative Review of Applications, Challenges, and Future Directions
Next Article in Special Issue
Radiology Access in Rural Germany: A Nationwide Survey on Outpatient Imaging and Teleradiology
Previous Article in Journal
Lightweight Deep Learning Framework for Accurate Detection of Sports-Related Bone Fractures
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
Diagnostics
Volume 15
Issue 3
10.3390/diagnostics15030272
diagnostics-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Article

Ultrasound-Guided Vacuum-Assisted Excision (VAE) in Breast Lesion Management: An Experimental Comparative Study of Two Different VAE Devices Across Various Aspiration Levels and Window Sizes

by
Serena Carriero
1,
Maurizio Cè
2,
Matilde Pavan
2,*,
Mariassunta Roberta Pannarale
2,
Giulia Quercioli
2,
Sveva Mortellaro
2,
Alessandro Liguori
1,
Maria Cosentino
1,
Maria Iodice
1,
Marta Montesano
1,
Giulia Querques
1,
Carolina Lanza
1,
Salvatore Alessio Angileri
1,
Pierpaolo Biondetti
1,
Filippo Pesapane
3,
Gianpaolo Carrafiello
1,4 and
Sonia Santicchia
1
1
Radiology Department, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Via Francesco Sforza 35, 20122 Milan, Italy
2
Postgraduate School in Radiodiagnostics, Università degli Studi di Milano, Via Festa del Perdono 7, 20122 Milan, Italy
3
Breast Imaging Division, Radiology Department, IEO European Institute of Oncology IRCCS, 20141 Milan, Italy
4
Department of Oncology and Hematology-Oncology, Università degli Studi di Milano, Via Festa del Perdono 7, 20122 Milan, Italy
*
Author to whom correspondence should be addressed.
Diagnostics 2025, 15(3), 272; https://doi.org/10.3390/diagnostics15030272
Submission received: 6 December 2024 / Revised: 20 January 2025 / Accepted: 21 January 2025 / Published: 24 January 2025
(This article belongs to the Special Issue Recent Advances in Diagnostic and Interventional Radiology)
Browse Figures
Versions Notes

Abstract

Background/Objectives: Vacuum-assisted excision (VAE) is a minimally invasive technique for breast tumor treatment, offering precision, comfort, and quick recovery. It is widely used for benign breast lesions and is playing an increasingly important role in the therapeutic management of non-surgical patients or patients who refuse surgery. Optimal outcomes require an understanding of device features to tailor treatment to each lesion. The Mammotome® Elite 10G operates in a fixed mode, while the Mammotome® Revolve EX 8G offers multiple aspiration levels and aperture windows for greater versatility. This study analyzed the specimen features (weight and length), comparing the weight obtained from two different VAE systems to aid the appropriate selection of a device based on the clinical setting. It also determined the number of specimens needed to achieve the 4 g diagnostic threshold. Methods: The Mammotome® Elite 10G and the Mammotome® Revolve EX were evaluated under controlled conditions. For Mammotome® Revolve EX, combinations of five aspiration levels and three aperture lengths (12 mm, 18 mm, and 25 mm) were tested. Twelve samples were collected from a chicken breast phantom for each setting. Specimen weights and the minimum excisions required to reach the 4 g threshold were analyzed. Results: The mean weight per sample for the Mammotome® Elite 10G was 0.16 ± 0.04 g. For the Mammotome® Revolve EX, the weights increased with aperture size and aspiration level, ranging from a minimum of 0.132 ± 0.028 g (a window length of 12 mm and aspiration level 1) to a maximum of 0.407 ± 0.055 g (a window length of 25 mm and aspiration level 5). The 25 mm window at aspiration level 5 achieved the 4 g threshold in as few as 10 samples. By comparison, the Mammotome® Elite required up to 26 samples. Conclusions: Compared to the Mammotome Elite, Mammotome® Revolve EX offers superior versatility and efficiency, reducing patient discomfort by minimizing the required samples. Its technical advantages make it a valuable tool for both diagnostic and therapeutic applications.
Keywords: breast; sample volume; vacuum-assisted biopsy; vacuum-assisted excision; breast cancer; breast benign lesions; B3 breast; sample volume; vacuum-assisted biopsy; vacuum-assisted excision; breast cancer; breast benign lesions; B3

Share and Cite

MDPI and ACS Style

Carriero, S.; Cè, M.; Pavan, M.; Pannarale, M.R.; Quercioli, G.; Mortellaro, S.; Liguori, A.; Cosentino, M.; Iodice, M.; Montesano, M.; et al. Ultrasound-Guided Vacuum-Assisted Excision (VAE) in Breast Lesion Management: An Experimental Comparative Study of Two Different VAE Devices Across Various Aspiration Levels and Window Sizes. Diagnostics 2025, 15, 272. https://doi.org/10.3390/diagnostics15030272

AMA Style

Carriero S, Cè M, Pavan M, Pannarale MR, Quercioli G, Mortellaro S, Liguori A, Cosentino M, Iodice M, Montesano M, et al. Ultrasound-Guided Vacuum-Assisted Excision (VAE) in Breast Lesion Management: An Experimental Comparative Study of Two Different VAE Devices Across Various Aspiration Levels and Window Sizes. Diagnostics. 2025; 15(3):272. https://doi.org/10.3390/diagnostics15030272

Chicago/Turabian Style

Carriero, Serena, Maurizio Cè, Matilde Pavan, Mariassunta Roberta Pannarale, Giulia Quercioli, Sveva Mortellaro, Alessandro Liguori, Maria Cosentino, Maria Iodice, Marta Montesano, and et al. 2025. "Ultrasound-Guided Vacuum-Assisted Excision (VAE) in Breast Lesion Management: An Experimental Comparative Study of Two Different VAE Devices Across Various Aspiration Levels and Window Sizes" Diagnostics 15, no. 3: 272. https://doi.org/10.3390/diagnostics15030272

APA Style

Carriero, S., Cè, M., Pavan, M., Pannarale, M. R., Quercioli, G., Mortellaro, S., Liguori, A., Cosentino, M., Iodice, M., Montesano, M., Querques, G., Lanza, C., Angileri, S. A., Biondetti, P., Pesapane, F., Carrafiello, G., & Santicchia, S. (2025). Ultrasound-Guided Vacuum-Assisted Excision (VAE) in Breast Lesion Management: An Experimental Comparative Study of Two Different VAE Devices Across Various Aspiration Levels and Window Sizes. Diagnostics, 15(3), 272. https://doi.org/10.3390/diagnostics15030272

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

Article Metrics

Back to TopTop